Tag: spinal cord injury

A hydrogel restores breathing after spinal cord injury in animal models

The use of a hydrogel after spinal cord injury is responsible for the restoration of independent breathing control in rats, according to research recently...

Experimental drug restores some bladder function after spinal cord injury

An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by...
Stem cells

NSI-566 stem cell therapy confers neurological improvement in spinal cord injury...

Intraspinal injections of human spinal cord-derived neural stem cells are well tolerated in a Phase I study of four patients with thoracic (T2–T12) ASIA-A...

Reprogrammed stem cell-derived neurons survive long-term in pigs with spinal cord...

Using stem cell derived neuronal cells reprogrammed from genetically identical animals eliminated the need for immunosuppression measures. A major hurdle to using neural stem cells...

Scientists map key brain-to-spinal cord nerve connections for voluntary movement

Researchers trying to help people suffering from paralysis after a spinal cord injury or stroke mapped critical brain-to-spinal cord nerve connections that drive voluntary...
Stem cells

New study offers hope for recovered motor function in patients with...

  Researchers report the successful use of a novel therapeutic strategy to enhance forelimb recovery in mice with chronically injured spinal cords. The findings were...
Paralysed Veterans of America

Grant applications for spinal cord injury or disease now open from...

Paralyzed Veterans of American (Paralyzed Veterans) has announced the launch of its 2018 Education and Training Foundation grant cycle. Applications for awards up to...
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Non-antibiotic strategy might prevent infections in patients with spinal cord injuries

New research led by The Ohio State University Wexner Medical Center, Columbus, USA, has found a potential non-antibiotic therapeutic strategy to prevent infections in...

Two new patients convert in Invivo Therapeutics’ INSPIRE trial

Invivo Therapeutics has provided an update on the progress of the company’s INSPIRE study (Invivo Study of Probable Benefit of the Neuro-Spinal Scaffold for...
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New surgical strategy offers hope for repairing spinal injuries

Recently, scientists in the UK and Sweden developed a surgical technique to reconnect sensory neurons to the spinal cord after traumatic spinal injuries. They...
Mouse

Positive pre-clinical results for Scholar Rock’s SRK-015 therapy in spinal cord...

Data presented at the 35th Annual National Neurotrauma Symposium (Neurotrauma 2017; 9–12 July, Snowbird, USA) have demonstrated beneficial effects for SRK-015 antibody therapy (Scholar...

First UK centre joins Invivo Therapeutics’ INSPIRE study

James Cook University Hospital in Middlesbrough, UK,  has been added as the country’s first clinical site for Invivo Therapeutics’ INSPIRE study (InVivo Study of...

Two InVivo Therapeutics INSPIRE patients convert AIS grade

InVivo Therapeutics has announced that two patients in the INSPIRE study of the Neuro-Spinal Scaffold have improved from sensory incomplete AIS B spinal cord...

New patient enrolled in InVivo Therapeutics’ INSPIRE study

InVivo Therapeutics has announced that a new patient has been enrolled into the INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold...

New patient enrolled in InVivo Therapeutics INSPIRE study

A new patient has been enrolled into InVivo Therapeutics' INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic...

Neurostimulation protocol reduces spasticity in spinal cord injury

Spasticity is a common disorder experienced by patients with spinal cord injuries (SCI). Previous studies have shown that excitatory repetitive transcranial magnetic stimulation (rTMS)...

InVivo to include international registry data in sister study to INSPIRE

InVivo Therapeutics has announced that data from the Christopher & Dana Reeve Foundation NACTN Registry will be included in the Contemporary Thoracic SCI registry...

New patient enrolled in InVivo INSPIRE study

A new patient has been enrolled into InVivo Therapeutics’ INSPIRE Study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic...

WWII chemical-weapon antidote shows promise as treatment for spinal cord injury

A drug developed during World War II as an antidote for a chemical warfare agent has been found to be effective at suppressing a...
Mouse

Discovery offers new hope to repair spinal cord injuries

Scientists at the Gladstone Institutes (San Francisco, USA) have created a special type of neuron from human stem cells that could potentially repair spinal...

First-in-human stem cell clinical trial for spinal injury expands

A first-in-human trial has been expanded to add four more qualifying participants with chronic cervical injuries involving C5-C7 vertebrae. Launched in 2014 with the...

InVivo Therapeutics announces first Canadian site for cervical spinal cord injury...

InVivo Therapeutics has received approval from the Toronto Western Hospital’s Research Ethics Board to enrol patients as part of its cervical spinal cord injury...

Seventh InVivo Therapeutics INSPIRE patient converts AIS grade

InVivo Therapeutics has announced that the patient enrolled in January in the INSPIRE study of the Neuro-spinal scaffold has improved from a complete AIS...

InVivo Therapeutics announces new cervical spinal cord injury study

Health Canada has approved Invivo Therapeutics’ Investigational Testing Authorization application to commence a clinical study of the Neuro-spinal scaffold in patients with acute, complete...

InVivo Therapeutics enrols Keck Hospital patient into INSPIRE study

A new patient has been enrolled into InVivo Therapeutics’ INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic...

Report details plethora of serious health problems faced by spinal cord...

Paralysis is just one of the many serious health problems faced by patients who suffer spinal cord injuries, according to a report according to...

Early data demonstrate motor function improvement for spinal cord stem cell...

A new therapy to treat spinal cord injuries in people who have lost all motor and sensory function below the injury site has shown...

Sixth INSPIRE patient improves ASIA score

An Invivo Therapeutics INSPIRE study patient enrolled in December 2016 has improved from a complete ASIA A spinal cord injury to an incomplete ASIA...

Researchers determine algorithm for bionic hand treatment

No longer only an image conjured by science fiction, bionic hands can return functionality in cases of traumatic nerve and muscle loss. A new...

PixarBio establishes research centre focusing on spinal cord injury treatment

PixarBio—developers of NeuroRelease, a morphine replacement, non-opioid pain treatment—has established the JP Reynolds Research Center in Woburn, USA. The lab will focus on research and...

Tenth patient enrolled in InVivo Therapeutics’ INSPIRE study

A new patient with a T8-9 fracture dislocation injury has been enrolled into InVivo Therapeutics’ INSPIRE Study (InVivo Study of Probable Benefit of the...

Canine study suggests neurotoxin monitoring could be used to personalise spinal...

Researchers have developed a urine test revealing the presence of a neurotoxin that likely worsens the severity and pain of spinal cord injuries. According...

New participant enrolled in Invivo Therapeutics’ INSPIRE study

InVivo Therapeutics has announced that a new patient has been enrolled into the INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold...

Gut microbiome changes could exacerbate spinal cord injury effects

Researchers from the Ohio State University (Columbus, USA) have discovered that spinal cord injury alters the type of bacteria living in the gut, and...

US$5 million granted to spinal cord injury robotics research project

Studies have shown that activity-based interventions can offer a promising approach to the improvement of motor function following spinal cord injury. Sunil Agrawal, professor...

First injection of AST-OPC1 stem cells for spinal cord injury takes...

A team of doctors from Keck Medical Center of the University of Sourthern California (Los Angeles, USA) have become the first in the US state...

Paraplegic patients regain some feeling, movement after using brain-machine interfaces

Eight people who have spent years paralysed from spinal cord injuries have regained partial sensation and muscle control in their lower limbs after training...

Health behaviours and management critical for spinal cord injury patients

According to the National Spinal Cord Injury Statistical Center, there are approximately 282,000 people currently living with a spinal cord injury in the USA. “Spinal...