Tag: spinal cord injury

Onward reports positive study results in restoring arm and hand function...

Onward Medical recently announced that the Up-LIFT pivotal study evaluating its non-invasive spinal cord stimulation (SCS) ARC-EX therapy achieved its primary effectiveness endpoint of...

Researchers discover neural plastic changes that improve functional recovery after cervical...

Spinal cord and brain injury researchers at Indiana University School of Medicine (Indianapolis, USA), are studying new alternatives to promote functional recovery after a...

SATURN study highlights favourable outcomes for NeuorAiD in spinal cord injury...

NeuroAiD (MLC601/MLC901; Moleac) has a favourable safety profile and promising benefits as an add-on therapy to patients suffering from severe spinal cord injuries (SCIs)...

RECODE-DCM: Global consensus reached on degenerative cervical myelopathy as single unifying...

A global, multi-stakeholder consensus process involving those with lived experience has selected degenerative cervical myelopathy (DCM) as the single unifying term for a progressive...

Oligodendrocyte progenitor cells can be safely administered to patients in the...

Oligodendrocyte progenitor cells (LCTOPC1; Lineage Cell Therapeutics) can be safely administered to participants in the subacute period after cervical spinal cord injury (SCI), according...

Enrolment completed in ONWARD’s LIFT Home study

ONWARD Medical has announced that it has completed enrolment in the LIFT Home study, which is designed to evaluate the safety and performance of...

InVivo Therapeutics announces full enrolment for INSPIRE 2.0 acute spinal cord...

InVivo Therapeutics has completed enrolment in the INSPIRE 2.0 study for patients with acute spinal cord injury. The 20-patient study is a randomised, controlled...

ONWARD announces first-in-human use of its ARC implantable neurostimulator for spinal...

ONWARD Medical has announced the first patient enrolment in the HemON study and first-in-human use of the company’s ARC implantable pulse generator (IPG), which is...

First participants enrolled in ONWARD’s LIFT Home study

ONWARD has begun enrolment in the LIFT Home study, which is designed to examine the safety and performance of its ARCEX Therapy for spinal cord...

Novoron Bioscience raises US$3 million to boost neuroregeneration therapy for spinal...

Novoron Bioscience has secured US$3 million in seed funding which will go towards advancing the development of its of neuroregeneration therapy for spinal cord...

Precise blood pressure control may aid patient recovery from spinal cord...

High or low blood pressure in patients undergoing surgery to repair a spinal cord injury may contribute to poorer outcomes and maintaining an optimal...

Neuroplast announces successful clinical Phase I trial with Neuro-Cells stem cell...

Dutch biotech company, Neuroplast, and the Hospital Nacional de Parapléjicos de Toledo in Spain have announced positive clinical Phase I results after analysis of ten patients...

Existing guidelines to change as research shows early surgical decompression following...

Surgical decompression within 24 hours of acute spinal cord injury (SCI) improves neurological recovery, and current guidelines on surgical management of SCI are being reviewed...

Surgery is associated with a greater likelihood of neurologic recovery in...

Brian Goh (Boston, USA) speaks to Spinal News International about the results of a study that aimed to better understand the impact of surgical...

Activity-based rehabilitation interventions are ‘effective in improving function’ in patients with...

Activity-based rehabilitation interventions, including transcranial magnetic stimulation, functional electrical stimulation, and robotic-assisted treadmill training are effective in improving function in patients with spinal cord...

IU School of Medicine researchers discover new potential for functional recovery...

Researchers at Indiana University School of Medicine (Indianapolis, USA) have announced the successful reprogramming of a glial cell type in the central nervous system...

Lineage set for clinical testing with OPC transplant therapy for spinal...

Biotechnology outfit Lineage Cell Therapeutics has announced that it will return to clinical testing with its investigational allogeneic oligodendrocyte progenitor cell (OPC) transplant therapy...

ONWARD receives breakthrough device designation for ARC-IM platform

ONWARD has announced the that it has received breakthrough device designation status from the US Food and Drug Administration (FDA) for their ARC-IM platform...

First patient enrolled in Up-LIFT safety and effectiveness trial of ARC...

ONWARD has announced that the first patient has been enrolled in a pivotal trial evaluating its ARC Therapy, according to a company press release....

Spinal cord injury patient regains ability to walk following electrical and...

The use of electrical and magnetic stimulation simultaneously has shown promising results and even helped a spinal cord injury patient regain the ability to walk.   The simultaneous stimulation...

Dorsal root ganglion stimulation evokes motor responses in patients with complete...

Bilateral L4 dorsal root ganglion (DRG) stimulation has been shown to evoke strong and reproducible motor responses in the upper leg in patients with...

Acute, severe spinal cord injury: Monitoring from the injury to improve...

Marios Papadopoulos and Samira Saadoun write in Spinal News International about the ISCoPE trial, which aimed to develop techniques to continuously monitor the pressure...

3D printed implant promotes nerve cell growth to treat spinal cord...

For the first time, researchers at University of California San Diego School of Medicine and Institute of Engineering in Medicine (La Jolla, USA) have...
How Cyclists get spinal injuries

A worrying trend in the spine centre referrals of cyclists

  Research that highlights a worrying trend between cycling and spinal trauma has recently been published in The Surgeon. Although the authors of the paper,...
suicide

Spinal injuries in suicidal jumpers “differ in many aspects” to non-suicidal...

New research outlines how spinal injuries in suicidal jumpers differ from those in non-suicidal patients with regard to patient demographics, mental health condition, injury...
Quality

Quality of life after spinal cord injury: Having independent mobility makes...

Independence in mobility is the single most important factor affecting quality of life in patients with traumatic spinal cord injury, reports a study in the American Journal of Physical Medicine &...

New therapy spurs nerve fibres to regrow through scar tissue and...

Neuroscientists at UCLA, Harvard University and the Swiss Federal Institute of Technology have identified a three-pronged treatment that triggers axons to regrow after complete...
Immune

The first immune-evasive gene therapy used to treat spinal cord injury...

A novel immune-evasive gene therapy has restored skilled grasping function in paralysed rats, allowing treated rodents to independently reach for and pick up sugar...

A hydrogel restores breathing after spinal cord injury in animal models

The use of a hydrogel after spinal cord injury is responsible for the restoration of independent breathing control in rats, according to research recently...

Experimental drug restores some bladder function after spinal cord injury

An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by...
Stem cells

NSI-566 stem cell therapy confers neurological improvement in spinal cord injury...

Intraspinal injections of human spinal cord-derived neural stem cells are well tolerated in a Phase I study of four patients with thoracic (T2–T12) ASIA-A...

Reprogrammed stem cell-derived neurons survive long-term in pigs with spinal cord...

Using stem cell derived neuronal cells reprogrammed from genetically identical animals eliminated the need for immunosuppression measures. A major hurdle to using neural stem cells...

Scientists map key brain-to-spinal cord nerve connections for voluntary movement

Researchers trying to help people suffering from paralysis after a spinal cord injury or stroke mapped critical brain-to-spinal cord nerve connections that drive voluntary...
Stem cells

New study offers hope for recovered motor function in patients with...

  Researchers report the successful use of a novel therapeutic strategy to enhance forelimb recovery in mice with chronically injured spinal cords. The findings were...
Paralysed Veterans of America

Grant applications for spinal cord injury or disease now open from...

Paralyzed Veterans of American (Paralyzed Veterans) has announced the launch of its 2018 Education and Training Foundation grant cycle. Applications for awards up to...
Mouse

Non-antibiotic strategy might prevent infections in patients with spinal cord injuries

New research led by The Ohio State University Wexner Medical Center, Columbus, USA, has found a potential non-antibiotic therapeutic strategy to prevent infections in...

Two new patients convert in Invivo Therapeutics’ INSPIRE trial

Invivo Therapeutics has provided an update on the progress of the company’s INSPIRE study (Invivo Study of Probable Benefit of the Neuro-Spinal Scaffold for...
Mouse

New surgical strategy offers hope for repairing spinal injuries

Recently, scientists in the UK and Sweden developed a surgical technique to reconnect sensory neurons to the spinal cord after traumatic spinal injuries. They...
Mouse

Positive pre-clinical results for Scholar Rock’s SRK-015 therapy in spinal cord...

Data presented at the 35th Annual National Neurotrauma Symposium (Neurotrauma 2017; 9–12 July, Snowbird, USA) have demonstrated beneficial effects for SRK-015 antibody therapy (Scholar...

First UK centre joins Invivo Therapeutics’ INSPIRE study

James Cook University Hospital in Middlesbrough, UK,  has been added as the country’s first clinical site for Invivo Therapeutics’ INSPIRE study (InVivo Study of...

Two InVivo Therapeutics INSPIRE patients convert AIS grade

InVivo Therapeutics has announced that two patients in the INSPIRE study of the Neuro-Spinal Scaffold have improved from sensory incomplete AIS B spinal cord...

New patient enrolled in InVivo Therapeutics’ INSPIRE study

InVivo Therapeutics has announced that a new patient has been enrolled into the INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold...

New patient enrolled in InVivo Therapeutics INSPIRE study

A new patient has been enrolled into InVivo Therapeutics' INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic...

Neurostimulation protocol reduces spasticity in spinal cord injury

Spasticity is a common disorder experienced by patients with spinal cord injuries (SCI). Previous studies have shown that excitatory repetitive transcranial magnetic stimulation (rTMS)...

InVivo to include international registry data in sister study to INSPIRE

InVivo Therapeutics has announced that data from the Christopher & Dana Reeve Foundation NACTN Registry will be included in the Contemporary Thoracic SCI registry...

New patient enrolled in InVivo INSPIRE study

A new patient has been enrolled into InVivo Therapeutics’ INSPIRE Study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic...

WWII chemical-weapon antidote shows promise as treatment for spinal cord injury

A drug developed during World War II as an antidote for a chemical warfare agent has been found to be effective at suppressing a...
Mouse

Discovery offers new hope to repair spinal cord injuries

Scientists at the Gladstone Institutes (San Francisco, USA) have created a special type of neuron from human stem cells that could potentially repair spinal...

First-in-human stem cell clinical trial for spinal injury expands

A first-in-human trial has been expanded to add four more qualifying participants with chronic cervical injuries involving C5-C7 vertebrae. Launched in 2014 with the...

InVivo Therapeutics announces first Canadian site for cervical spinal cord injury...

InVivo Therapeutics has received approval from the Toronto Western Hospital’s Research Ethics Board to enrol patients as part of its cervical spinal cord injury...

Seventh InVivo Therapeutics INSPIRE patient converts AIS grade

InVivo Therapeutics has announced that the patient enrolled in January in the INSPIRE study of the Neuro-spinal scaffold has improved from a complete AIS...

InVivo Therapeutics announces new cervical spinal cord injury study

Health Canada has approved Invivo Therapeutics’ Investigational Testing Authorization application to commence a clinical study of the Neuro-spinal scaffold in patients with acute, complete...

InVivo Therapeutics enrols Keck Hospital patient into INSPIRE study

A new patient has been enrolled into InVivo Therapeutics’ INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold for Safety and Neurologic...

Report details plethora of serious health problems faced by spinal cord...

Paralysis is just one of the many serious health problems faced by patients who suffer spinal cord injuries, according to a report according to...

Early data demonstrate motor function improvement for spinal cord stem cell...

A new therapy to treat spinal cord injuries in people who have lost all motor and sensory function below the injury site has shown...

Sixth INSPIRE patient improves ASIA score

An Invivo Therapeutics INSPIRE study patient enrolled in December 2016 has improved from a complete ASIA A spinal cord injury to an incomplete ASIA...

Researchers determine algorithm for bionic hand treatment

No longer only an image conjured by science fiction, bionic hands can return functionality in cases of traumatic nerve and muscle loss. A new...

PixarBio establishes research centre focusing on spinal cord injury treatment

PixarBio—developers of NeuroRelease, a morphine replacement, non-opioid pain treatment—has established the JP Reynolds Research Center in Woburn, USA. The lab will focus on research and...

Tenth patient enrolled in InVivo Therapeutics’ INSPIRE study

A new patient with a T8-9 fracture dislocation injury has been enrolled into InVivo Therapeutics’ INSPIRE Study (InVivo Study of Probable Benefit of the...

Canine study suggests neurotoxin monitoring could be used to personalise spinal...

Researchers have developed a urine test revealing the presence of a neurotoxin that likely worsens the severity and pain of spinal cord injuries. According...

New participant enrolled in Invivo Therapeutics’ INSPIRE study

InVivo Therapeutics has announced that a new patient has been enrolled into the INSPIRE study (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold...

Gut microbiome changes could exacerbate spinal cord injury effects

Researchers from the Ohio State University (Columbus, USA) have discovered that spinal cord injury alters the type of bacteria living in the gut, and...

US$5 million granted to spinal cord injury robotics research project

Studies have shown that activity-based interventions can offer a promising approach to the improvement of motor function following spinal cord injury. Sunil Agrawal, professor...

First injection of AST-OPC1 stem cells for spinal cord injury takes...

A team of doctors from Keck Medical Center of the University of Sourthern California (Los Angeles, USA) have become the first in the US state...

Paraplegic patients regain some feeling, movement after using brain-machine interfaces

Eight people who have spent years paralysed from spinal cord injuries have regained partial sensation and muscle control in their lower limbs after training...

Health behaviours and management critical for spinal cord injury patients

According to the National Spinal Cord Injury Statistical Center, there are approximately 282,000 people currently living with a spinal cord injury in the USA. “Spinal...