The results of a recent study suggest that elective one to three level anterior cervical discectomy with fusion surgeries (ACDFs) at physician-owned hospitals have significant cost savings, while having lower odds of experiencing 90-day medical complications and readmissions. These...
Early postoperative results of a double blind randomised clinical trial demonstrate the benefit of local intraoperative corticosteroids (LIC) delivered with an absorbable haemostatic matrix to prophylactically reduce dysphagia following anterior cervical discectomy and fusion (ACDF) surgery. The findings were...
According to new research, certain ratios of correction of cervical parameters contribute to improving neck disability. The study, authored by Katherine E Pierce (NYU Langone Medical Centre, New York, USA) and colleagues, was recently nominated for Best Paper at...
Brainlab has unveiled Loop-X, the first mobile intraoperative imaging robot, at NASS 2019 (34th Annual North American Spine Society Meeting; 25–28 September, Chicago, USA). Loop-X sits at the core of the Brainlab Digital Surgery portfolio for the rapidly evolving...
Medtronic today announced US Food and Drug Administration (FDA) approval of a prospective, randomised pivotal clinical trial for the use of Infuse bone graft in transforaminal lumbar interbody fusion (TLIF) spine procedures. "The potential to expand the indications for use...
Alphatec Holdings announced today the commercial release of its IdentiTi TLIF Posterior Oblique Titanium Interbody Implant System (IdentiTi PO) for transforaminal lumbar interbody fusion procedures. The launch of IdentiTi (TLIF) PO follows successful alpha evaluations that began in January 2019...
RTI Surgical will showcase its body of clinical data at the 34th Annual Meeting of the North American Spine Society Annual Meeting (NASS 2019; 25–28 September, Chicago, USA). “RTI is proud to not only be a partner of choice for...
The Johnson & Johnson Medical Devices Companies today announced that DePuy Synthes has launched the CONDUIT Interbody Platform with EIT Cellular Titanium Technology, further expanding its comprehensive offering to treat degenerative spine disease. The portfolio, which includes 3D printed...
ControlRad has announced the first clinical use of the ControlRad Trace system following its clearance by the US Food and Drug Administration. The initial procedures were performed at Niagara Falls Memorial Medical Center (Niagara Falls, USA) by Andrew Cappuccino,...
Highlights: Worldwide burnout survey "highlights the need for better interventional programmes" (p. 1) Intravenous ketorolac substantially reduces opioid use following lumbar spinal fusion (p. 1) Paul Sponseller, president elect of the Scoliosis Research Society, gives his highlights of IMAST...
AOSpine is the leading global academic spine community, creating, disseminating, and exchanging knowledge to promote excellence in patient care and outcomes. This supplement will explore what makes AOSpine unique as a spine society, and how it stays relevant for...
RTI Surgical has announced the first surgery using the HPS 2.0 Hybrid Performance System, a modular pedicle screw system used for mono- and multi-segmental rigid, hybrid or dynamic posterior stabilisation of the thoracolumbar spine. William Sears, a neurosurgeon and Fellow...
Fundamental Surgery has announced the expansion of their Global Medical Panel with Yousuf Khalifa, Ivan Wong, and Areena D’souza as their latest members. In their roles, they will they will provide scientific and clinical guidance in the development of...
For Lenke 1A curves between 45 and 65 degrees treated with low- versus high-implant density in adult idiopathic scoliosis (AIS) patients, a prospective, multicentre, randomised controlled study has shown equivalent percentage coronal curve correction. The Minimise implants maximise outcomes...
Medtronic has announced that the National Osteoporosis Foundation (NOF) supports the vertebral compression fracture (VCF) Care Pathway, a new evidence-based clinical care pathway developed by a multispecialty panel of experts to ensure osteoporotic VCF patients receive timely and...
Camber Spine has announced the launch of its first spinal implant designed and manufactured specifically for the oblique lumbar interbody fusion (OLIF) spine surgical procedure. This implant represents the fifth product in its distinctive, rapidly growing SPIRA device family....
Omar Ishrak, Medtronic’s chairman and CEO is to retire on 26 April 2020, following the end of the company’s current fiscal year. Also, the Medtronic Board of Directors has announced key leadership appointments as part of its multi-year, leadership...
A new study, published in the European Spine Journal, suggests that a computer-aided method has the potential for automatic Cobb angle measurement and scoliosis diagnosis on chest X-rays. As the Cobb angle is involved in therapeutic decisions of scoliosis,...
A meta-analysis, recently published in Osteoporosis International, has found that the application of percutaneous vertebroplasty (PVP) is safe and effective only in patients with acute osteoporotic vertebral compression fractures (OVCFs) having persistent and severe pain. The investigators recorded no...
Life Spine recently announced that it is now selling its Micro Invasive suite of products in thirty countries worldwide. New customers in Vietnam and South America have recently begun purchasing products from Life Spine’s broad product portfolio and Life Spine...
Nexxt Spine has released their Lordotic TLIF Oblique interbody into the market.  The product is designed for transforaminal lumbar interbody fusion (TLIF), the most frequently performed procedure in the field. Derived from the NEXXT MATRIXX family of products, Lordotic TLIF...
Bad posture among UK office employees is a nationwide epidemic. Sitting at desks all day, slouching over computers and a general sedentary lifestyle has led one in five Brits to give up their job or reduce hours because of...
DiscGenics has announced that the US Food and Drug Administration (FDA) has granted fast track designation for its investigational cell therapy, IDCT, currently being evaluated in regulator-allowed clinical trials in the USA and Japan for the reduction in pain...
According to a press release, SurGenTec has received FDA clearance for a neurostimulation indication for their ALARA Neuro Access Needle Kit. The ALARA system is used for targeting and assisting in cannulating a pedicle. Targeting needles are generally the...
The Congress of Neurological Surgeons (CNS) recently awarded their Top Paper of the Year and Spine Section Paper of the Year to an analysis of 10-year results from a prospective, randomised, clinical trial comparing cervical disc arthroplasty (CDA) to...
Zimmer Biomet recently announced US Food and Drug Administration (FDA) approval for The Tether for treatment of scoliosis, providing a fusion-less alternative for young patients requiring surgery. The current surgical treatment for scoliosis is an invasive operation involving large incisions, extensive soft...
Medtronic has completed its acquisition of Titan Spine, which has a range of interbody fusion devices that feature unique surface technology. A press release reports that the acquisition provides opportunities to bundle interbodies, screws, rods, biologics, and “enabling” technologies,...
A recent study developed models capable of “excellent discrimination” between operative and non-operative management of patients based solely on baseline preoperative values. According to the authors, patient-reported outcome measures (PROMs) were particularly instrumental in making these predictions, and they...
While robotic technology is still in its infancy, current evidence suggests a promising future for its application in spine surgery, argue Ronald A Lehman and Nathan J Lee. Here, for Spinal News International, they discuss the results of recent...
Spineology has announced the launch of the Duo Angled Instrumentation System. The angled instrumentation supplements the Duo Lumbar Interbody Fusion System and allows surgeons to efficiently address the L4–L5 disc space in cases where the iliac crest prevents collinear...
Bernhard Meyer (Munich, Germany) and Henry Halm (Neustadt, Germany) discuss spinal navigation—specifically any increased risk in radiation exposure and if that risk is offset by the potential benefit of an increase in precision of pedicle screw placement. The two physicians...
Alphatec Holdings announced today the commercial release of InVictus minimally invasive, or MIS, SingleStep K-wireless implant delivery system. By completely eliminating the requirement for K-wires in a percutaneous pedicle fixation procedure, SingleStep limits the potential complications associated with inadvertent...
DiscGenics today announced the first patients have been treated in its Japanese safety study, a clinical trial of IDCT for mild to moderate degenerative disc disease (DDD). The treatments took place at Tokai University School of Medicine in Kanagawa,...
The Medicrea Group announced today that it has received FDA clearance for Tulip Genesis, which completes its UNiD ASI platform technology. With the FDA clearance of the Tulip Genesis, Medicrea completes its UNiD ASI platform by providing a top loading...
President of the Scoliosis Research Society (SRS), Peter Newton (San Diego, USA), speaks to BLearning at IMAST 2019 (17 –20 July, Amsterdam, The Netherlands) about this year’s annual meeting, which “focused on innovation” and covered the “breadth of spinal surgery, not just spinal deformity...
Fernando Techy (Johnstown, USA), speaks to BLearning at IMAST 2019 (17–20 July, Amsterdam, The Netherlands) about longer-term trials of disc replacement which, according to Techy, has shown that “we are having less re-operations with disc replacement compared to fusion” and that “disk...
Paul Sponseller, president elect of the Scoliosis Research Society (SRS), talks to Spinal News International about the 26th International Meeting on Advanced Spine Techniques (IMAST 2019; 17–20 July, Amsterdam, The Netherlands). The mission of IMAST was to complement the...
Orthofix Medical recently announced that it has named Jon Serbousek as president of its Global Spine business effective 5 August, 2019, and the successor to Brad Mason, the company’s retiring president and chief executive officer (CEO), to be effective...
SeaSpine has announced the limited commercial launch of the Mariner Outrigger Revision System. Mariner Outrigger is an implant system providing surgeons a high level of versatility for multiple revision applications. As an adjunct to the Mariner Posterior Fixation system, Mariner...
In a recent, award-winning study, 266 million individuals worldwide (3.63%) were found to have degenerative spine disease and low back pain annually. “Significantly,” the investigators note, “data quality is higher in high-income countries, making overall quantification in low- and...
Kenneth Cheung (Hong Kong) speaks to BLearning at IMAST 2019 (17 –20 July, Amsterdam) about how growth modulation techniques can be used to treat spinal deformity in young children. Traditionally, spinal deformity has been corrected using spinal fusion. However,...
The presence of a sleep disorder has a "significant and unique effect" on back pain-related healthcare use—beyond the impact of pain intensity, disability, and other factors, according to a study recently published in Spine. Authors Daniel Rhon (Brooke Army...
The results of a recent study indicate that anterior column realignment (ACR) via a lateral approach allows for the normalisation of spinopelvic parameters without additive complication risk when compared to lateral lumbar interbody fusion (LLIF). Presenting author Praveen Mummaneni...
Early results of a double-blind, randomised, placebo-controlled trial show that intravenous ketorolac results in a “substantial reduction” in opioid use and improved pain control compared to placebo and intravenous acetaminophen. In addition, the investigators note a trend towards decreased...
Implanet has announced that its Jazz Lock technology, which is an integral part of its Jazz solutions platform, has been granted a patent in the USA. A major component of the broadest range of band products on the market, Jazz...
Life Spine announced today that the US Food and Drug Administration (FDA) has provided additional 510(k) market clearance for the ProLift expandable spacer system. “The new 8–10mm widths of the ProLift expandable spacer system are essential additions to our innovative...
Alphatec Holdings has announced the commercial release of InVictus, a spinal fixation platform designed to address a range of pathologies through a minimally invasive (MIS), open, or hybrid surgical approach. “The InVictus platform incorporates and improves upon the learnings...
MiRus has announced US Food and Drug Administration (FDA) 510(k) clearance of the GALILEO spine alignment monitoring system, a non-optical, wireless, real-time measurement system for segmental and global sagittal spine alignment. The GALILEO spine alignment monitoring system received the...
According to a press release, Centinel Spine has received Investigational Device Exemption (IDE) approval from the US Food and Drug Administration (FDA) to initiate a two-level clinical trial with two different ProDisc C Anterior Cervical Total Disc devices—ProDisc C...
Joimax has announced the official sales launch of its complete, CE-approved, EndoLIF product line. EndoLIF is an instrument set for endoscopic-assisted minimally invasive lumbar interbody fusion. As already announced and showcased at earlier events, the EndoLIF family consists of...
Results of a recent survey of 1,000 women (age 35–60) conducted by SI-Bone found that 86% of respondents are unaware that sacroiliac (SI) joint dysfunction is a leading cause of chronic lower back pain for women over 35 who...
SeaSpine has announced the full commercial launch of the Regatta Lateral System, featuring NanoMetalene technology. According to a press release, Regatta is a comprehensive, minimally invasive lateral interbody fusion system designed to efficiently and reproducibly treat the spine through indirect decompression and...
Warnings that ruled that capped training hours for medical residents at 80 hours per week would leave physicians-in-training unprepared for the challenges of independent practice have been shown to be largely unjustified in research published in the British Medical...
Observed patterns of cervical radiculopathy only followed the standard “Netter diagram” distribution in 54% of patients, and did not differ by the cervical level involved, in a recent study by Steven J McAnany (Hospital for Special Surgery, New York,...
Robert Lee (London, UK) tells Spinal News International why he prefers using computer navigation to free-hand technique in pedicle screw placement procedures. Lee explains that computer navigation can reduce surgeons' exposure to radiation and improve the accuracy and precision...
The US Food and Drug Administration (FDA) has granted Swiss devicemaker Icotec 510(k) clearance for its VADERone pedicle screw system, used for minimally-invasive and open spine surgeries. The device uses the company’s BlackArmor carbon/PEEK composite material, a carbon fibre...
NuVasive has announced the launch of its Pulse integrated technology platform. According to a press release, “Pulse is the first, single platform to include multiple technologies designed to help surgeons adopt more efficient, less disruptive surgical approaches in all...
Cerapedics has announced the expansion of the company's headquarters located in the Denver metropolitan area. Over the past 18 months, Cerapedics has grown from 16 to 44 employees in Colorado and is increasing its facility from 14,000 to 24,000...
The opening symposium at the 2019 Global Spine Congress (15–18 May, Toronto, Canada) focused on cutting edge updates in spine surgery. Scott Boden addressed the topic of biologics in spine surgery, detailing state of the art evidence and novel...
Redd Warburton, a senior executive search consultant, specialising in orthopaedics and spine, argues that while there are significant hurdles to overcome for robotics to be adopted within routine spinal surgery, robotics is here to stay. Robotics undoubtedly has a...
Relievant Medsystems recently announced the publication of the Level I INTRACEPT Study results in The Spine Journal. The INTRACEPT Study is a Level I, randomised, multicentre trial comparing the Intracept Procedure to non-surgical standard care. Based on the results...
Biogen today announced new results from the NURTURE study, adding data to the longest study of spinal muscular atrophy (SMA) in pre-symptomatic infants (n=25). These data reported, after up to 45.1 months of analysis, continue to demonstrate efficacy and...

NSpine 2019 live coverage

The NSpine Main Conference will focus on the entire spine during a series of lectures & workshops. We comprehensively cover the entire range of spinal conditions relevant to spine health care professionals.   Stay tuned.... We go live on Monday...
Medtronic today announced it has completed the acquisition of Titan Spine, a privately-held titanium spine interbody implant and surface technology company. A definitive acquisition agreement between the two companies was previously announced on 9 May 9 2019. The acquisition...
Fusion Robotics today announced the closing of a financing round for an undisclosed amount with lead investment by Alex Lukianov (Lukpartners) and Kevin Foley. The proceeds will be used to ready the company's spinal robotics platform to obtain regulatory clearance...
To enable upcoming regulatory filings, Medtronic has made public its partnership with Karl Storz, who have developed a system for endoscopic imaging. For the past four years, a press release reports, the two companies have partnered to seamlessly integrate...
Life Spine has announced that the US Food and Drug Administration (FDA) has provided 510(k) market clearance for the ProLift lateral expandable spacer system. “The ProLift lateral expandable spacer system is a significant addition to Life Spine’s rapidly growing expandable...
Gilda Giron was just 13 weeks pregnant when an ultrasound revealed her baby had myelomeningocele—the most severe form of open spina bifida, a birth defect that affects backbone development and can cause, among other things, debilitating neurological damage. “This was...
NYU Langone Health last month became the first centre in the USA to perform a discectomy with repair of a large annular defect using a titanium bone-anchored implant newly approved by the US Food and Drug Administration (FDA). The...
Boston Scientific has announced the close of its acquisition of Vertiflex, a privately-held company that developed and commercialised the Superion Indirect Decompression System, a minimally-invasive device used to improve physical function and reduce pain in patients with lumbar spinal stenosis...
Spinal neurosurgeon Todd H Lanman has become the first US doctor to perform a two-level artificial disc replacement surgery using the newly US Food & Drug Administration (FDA) approved M6-C device from Orthofix. He performed the procedure with his...
RTI Surgical today announced a milestone of 5,000 implants of Fortilink-C, -TS and -L interbody fusion (IBF) systems with TETRAfuse 3D technology in the USA. “In my over 500 implantations, I have been extremely satisfied with the Fortilink-TS and -C...
Implanet has announced successful results of the first surgeries using Jazz Cap in the USA. Following 510(k) clearance in March 2019, the first Jazz Cap procedures have been successfully completed by fellowship trained orthopaedic spine surgeon Chi Lim, in...
Medacta International recently announced its MySpine Midline Cortical (MC) platform has been recognised as this year’s “Best Healthcare Navigation / Robotics Solution” by MedTech Breakthrough. MySpine MC is the Medacta’s patient-matched, 3D printed solution in the midline cortical approach,...
RTI Surgical today announced MedTech Breakthrough has selected TETRAfuse 3D technology as the “Best New Technology Solution - Orthopedics” in their 2019 Awards Program. MedTech Breakthrough is an independent organisation recognising the top companies and solutions in the global...
Astura Medical and Academy Medical recently announced their partnership for contracting within the Department of Defense (DoD) and VA. According to a press release, Academy Medical’s goal is to provide sales channels, via contracts, to appropriate medical and surgical vendors,...
Collegiate football players have low rates of serious or disabling  injuries of the cervical spine, concludes an analysis of a National Collegiate Athletic Association (NCAA) database, reported in the journal Spine. The journal is published in the Lippincott portfolio by Wolters...
Misonix today announced that it received 510(k) clearance by the US Food and Drug Administration (FDA) for Nexus, its ultrasonic surgical platform. Misonix will commence the commercialisation of the Nexus platform in the USA in July. Nexus is an integrated...
Results of the CSM-Protect trial show that a six-week course of riluzole as an adjunct to surgical decompression for moderate-severe degenerative cervical myelopathy (DCM) has “no significant benefit” to the primary outcome of mJOA and “interesting effects” on three...
Globus Medical recently announced the launch of AERIAL, a minimally invasive expandable interspinous fixation system with independent locking plates. The expandable central core of AERIAL provides continuous distraction for indirect decompression and a customised patient fit. This is Globus...
Alphatec Holdings recently announced the commercial release of its IdentiTi-PC porous titanium interbody implant system for transforaminal lumbar interbody fusion procedures (TLIF). “The commercial launch of IdentiTi-PC demonstrates continued solid progress against our commitment to accelerate growth by compelling the...
According to a recent study, the low-virulent microorganisms frequently detected on pedicle screws by using sonication may be an important cause of implant loosening and failure. Additionally, the investigators found that a longer surgical duration increases the likelihood of...
Marios Papadopoulos and Samira Saadoun write in Spinal News International about the ISCoPE trial, which aimed to develop techniques to continuously monitor the pressure of the spinal cord at the injury site in the intensive care unit (ICU). They...

Ronald Bartels

A clinical professor of neurosurgery, Ronald Bartels talks to Spinal News International about his career. From his days at medical school to his appointment as chair of the Department of Neurosurgery at Radboud University Medical Center, he discusses how...
Globus Medical has announced the results of a clinical study that evaluated the versatility of ExcelsiusGPS robotic navigation system compared to traditional pedicle screw placement techniques. Published in the Journal of Robotic Surgery, “Robotic-assisted navigated minimally invasive pedicle screw...
EOS imaging has announced its fourth EOS system installation at the Hospital for Special Surgery (HSS; New York City, USA). HSS is the world’s largest academic medical centre dedicated to musculoskeletal health, performing more than 33,000 surgical procedures a...
Results of a worldwide survey indicate that the overall prevalence of burnout among spine surgeons is 30.6%. They suggest that factors linked with higher likelihood of burnout include working in North America, being in training as a fellow, and...
The first study to describe spinal trauma management and its outcomes in East Africa was recently published in the Journal of Neurosurgery: Spine. First authors Andreas Leidinger and Eliana E Kim, senior author Roger Härtl (Weill Cornell Brain and...
Joimax is showcasing its integrated navigation tracking and control system, Intracs, at this year’s Global Spine Congress (GSC; 15–18 May, Toronto, Canada). The company is also promoting the system at the annual meeting of the German Society of Neurosurgery...
Kaia Health has announced results from the first randomised controlled trial of its app-based therapy program for patients with non-specific low back pain. Detailed results of the study were published in the journal NPJ Digital Medicine and showed that...
Outgoing British Association of Spine Surgeons (BASS) president, Stuart Blagg (Aylesbury, UK), sits down with incoming president Sashin Ahuja (Cardiff, UK) at the BASS 2019 conference in Brighton to discuss Blagg’s achievements over the past two years as well...
Medtronic recently announced that it has entered into a definitive agreement pursuant to which it will acquire Titan Spine, a privately-held titanium spine interbody implant and surface technology company. The boards of directors of both companies have unanimously approved...
Boston Scientific today announced that it has entered into a definitive agreement to acquire Vertiflex, a privately-held company which has developed and commercialised the Superion Indirect Decompression System, a minimally-invasive device used to improve physical function and reduce pain...
Highlights: Cages in ACDF are associated with a higher non-union rate than allograft Advanced method of quantifying the cone of economy may allow practitioners to determine appropriate treatment options While the ASBMR taskforce report concludes that “no further trials...
Nicholas Theodore (Baltimore, USA) talks to Spinal News International about the benefits of robotics technology in spinal surgery including reducing radiation exposure to surgeons, improving accuracy and precision and ultimately allowing patients to get better faster. Theodore looks at...
At the 2019 meeting of the International Society for the Advancement of Spine Surgery (ISASS; 3–5 April, Anaheim, USA), Erik Wang of NYU Langone Health (New York, USA) presented the results of a study reviewing the rates of hospital-acquired...
Investigators found a higher rate of non-union associated with intervertebral cages than with allograft in a recent retrospective analysis, which led to the conclusion that allograft may be superior to cages in anterior cervical discectomy and fusion (ACDF). This...

Matthew Scott-Young

As the incoming president of the Spine Society of Australia, Matthew Scott-Young details how his experience as an Emergency Department intern sparked a life-long interest in spine care. He addresses current challenges, warning against the dangers of cost minimisation,...
Relievant Medsystems have announced the publication of 24-month results from the SMART trial in the International Journal of Spine Surgery. A total of 106 of the 128 treatment arm patients in the SMART trial completed 24-month follow up. Data...
Orthofix Medical today announced the first commercial implants of patients with the M6-C artificial cervical disc. The Center for Disc Replacement at Texas Back Institute (TBI) in Dallas, USA recently implanted four patients suffering from single-level cervical disc degeneration...
Winner of the Sanford J Larson Award, Nathan Xie, presented his research, "Use of artificial intelligence to improve surgical referrals in degenerative lumbar spine conditions", during the 2019 American Association of Neurological Surgeons Annual Scientific Meeting (AANS; 13–17 April,...
EOS imaging today introduced EOSlink, the company's new solution enabling the seamless integration of its EOSapps preoperative surgical planning software with intraoperative surgical solutions, such as navigation devices, robotics-based systems and custom spinal rod solutions. EOSapps is EOS imaging's suite...
A recent study conducted by Peter G Passias (NYU Langone Health, New York Spine Institute, New York, USA) and colleagues showed that male patients and patients with increased comorbidity severity experienced a greater length of hospital stay (LOS) after...
A new method to quantify the boundaries of Dubousset’s cone of economy, the centre of mass displacements, and the amount of sway within the cone of economy along with the energy expenditure for a specific patient, has been developed...
A recent taskforce report charged by the American Society for Bone and Mineral Research (ASBMR) concluded that current evidence does not support the routine use of vertebroplasty for the treatment of pain from vertebral fractures. However, as someone who...
A recent study found that a longer duration of preoperative radiculopathy symptoms in patients with degenerative cervical pathology is associated with worse health-related quality of life (HRQOL) outcome measures after 1–3 level anterior cervical discectomy and fusion (ACDF) surgery....
Optimal correction of sagittal alignment and improving a patient’s functional capacity can significantly influence postoperative frailty resolution, according to a recent study by Peter Passias (NY Spine Institute, New York, USA) and colleagues. According to the authors, the CD-FI...
Francis Lovecchio (Hospital for Special Surgery , New York, USA) recently gave a presentation on opioid consumption patterns after lumbar microdiscectomy or decompression at the 19th Annual Conference of the International Society for the Advancement of Spinal Surgery (ISASS;...
A recent study found that low back pain is significantly improved in 74% of patients immediately after surgery for lumbar spinal stenosis and that at two years, over two-thirds of patients continue to have significant relief of low back...
At the annual meeting of the International Society for the Advancement of Spinal Surgery (3–5 April, Anaheim, USA), Jack E Zigler (Texas Health Center for Diagnostics and Surgery, Texas Back Institute, Plano, USA) reported results which “strongly support” the...
Spineology has announced that two abstracts highlighting the company’s proprietary mesh technologies were presented during the 19th Annual Meeting of the International Society for the Advancement of Spine Surgery (ISASS; 3–5 April, Anaheim, USA). In a poster titled "Patient-reported outcomes...
Highlights: Single-level anterior cervical discectomy provides "solid alternative" to fusion or arthroplasty Banned in the USA: Petition calls for FDA to prohibit reprocessed pedicle screws N20: Spine in the spotlight at global meeting Expanding access to surgery on a...
Orthofix Medical today announced the full two-year outcomes from its US Investigational Device Exemption (IDE) study of the M6-C artificial cervical disc (Orthofix). Jack Zigler, orthopaedic spine surgeon at Texas Back Institute (Plano, USA) and an investigator in the study,...
New retrospective studies led by Charla Fischer, associate professor of orthopaedic surgery and director of quality and patient safety at NYU Langone’s Spine Center (New York, USA), show that the number of opioids taken before and during hospital stays...
Anterior cervical discectomy and fusion (ACDF), can be safely performed in an outpatient setting in select patients, according to a study at Hospital for Special Surgery (HSS; New York, USA). The research, titled, “A comparison of multilevel anterior cervical discectomy...
EOS imaging has announced installation of the first EOS system in the United Arab Emirates (UAE), located at the newly inaugurated King's College Hospital (Dubai, UAE) in January 2019. The new hospital, a joint venture of the Al Tayer Group,...
Eric Lamoutte and Kern Singh (Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, USA) discuss results of their recent study examining whether or not day of surgery affects length of stay and hospital charges following lumbar decompression. While...
It was recently announced that RTI Surgical has enrolled the first patient in its "Clinical evaluation of Fortilink interbody fusion device with TETRAfuse 3D technology in subjects with degenerative disc disease" (FORTE) study. FORTE is a prospective, multicentre post-market evaluation of...
Current evidence does not support the use of vertebroplasty for the treatment of pain from vertebral fractures, concludes a recent task force report charged by the American Society for Bone and Mineral Research (ASBMR) aimed at examining the efficacy...
SpinalCyte recently announced the issuance of new patents in the USA and Japan. The company’s patent portfolio now includes 39 US and international patents issued with over 100 patents pending focused on the clinical use of fibroblasts. The company...
A study at the Hospital for Special Surgery (HSS; New York, USA) found that a CT scan of the lumbar spine prior to surgery indicated that a significant number of patients had low bone density that was previously undiagnosed....
RTI Surgical has announced it has completed the acquisition of Paradigm Spine.  Paradigm Spine's primary product is the Coflex interlaminar stabilisation device. According to a press release, this is a “differentiated, minimally invasive motion preserving stabilisation implant that is FDA...
This advertorial has been sponsored by INVIBIO ™ Hyun W Bae, MD, is a medical director at The Spine Institute (Saint John’s Health Center, Santa Monica, USA) and professor of Surgery at Cedars-Sinai Medical Center (Los Angeles, USA). An orthopaedic...
Inspired Spine recently celebrated the grand opening of its concierge centre with a two day event that included a cadaver training lab at its Burnsville Total Spinal Health Center. The 120,000 sq. ft. three building campus is a testament...
The commissioner of the US Food and Drug Administration (FDA), Scott Gottlieb, has unexpectedly resigned after serving just shy of two years in the post. Gottlieb announced his intention to stand down in a letter to Alex Azar II, the...
Two-year results of a randomised controlled trial, published in the Journal of Bone and Joint Surgery, suggest that minimally invasive sacroiliac joint arthrodesis with triangular titanium implants is safe and more effective throughout two years in improving pain, disability, and...
The International Society for the Advancement of Spine Surgery (ISASS) recently issued a new bone grafting policy that features i‑FACTOR peptide enhanced bone graft (Cerapedics) as one of only two drug-device combination products approved by the US Food &...
Vertos Medical said it has received CE mark approval for its lumbar spinal stenosis (LSS) treatment device kit. According to a press release, the company's Mild device kit enables a minimally invasive procedure to remove the cause of stenosis through a...
Universal health is a top priority at the Weill Cornell Brain and Spine Centre in New York, USA. Their global neurosurgery programme, a collaborative project designed to improve access to surgery and surgical care across the world, has been...
Results of a double-blinded randomised controlled trial indicate that anterior cervical disc arthroplasty (ACDA) does not lead to a superior outcome in comparison to anterior cervical discectomy with fusion (ACDF) or anterior cervical discectomy (ACD) alone. Subsequent investigation involving...
Atlas Spine has announced the successful completion of its 50th surgical procedure and over 100 devices implanted with its new HiJak AC expandable cervical interbody fusion device. The company has now moved to its full product launch.   According to a...
OrthoPediatrics has announced the launch of BandLoc DUO, the latest addition to the BandLoc 5.5/6.0mm system. BandLoc is a temporary implant for use in orthopaedic surgery, intended to provide stabilisation as a bone anchor during the development of solid bony fusion...
It was announced recently that Alphatec has received 510(k) clearance from the US Food & Drug Administration (FDA) for its automated SafeOp neuromonitoring system for use in real-time intraoperative nerve location and health assessment. According to a press release, the technology of...
A recent study found that patients who presented with presurgical depressive symptoms reported more severe symptoms preoperatively and postoperatively. However, despite residual symptoms, these patients may benefit more from surgery than those without depressive symptoms. The results were presented...
Inspired Spine's H Abbasi has released a study presenting clinical, and radiological outcomes including fusion rates for oblique lateral lumbar interbody fusion (OLLIF). The study establishes, based upon a 300 plus patient population, that OLLIF is an extraordinary, safe,...
Life Spine has announced the initiation of the SIMPACT sacroiliac joint (SI) fixation outcomes study, with Keith Maxwell of Southeastern Sports Medicine and Orthopedics in Asheville, USA. SIMPACT is a cannulated and fenestrated screw, intended for sacroiliac joint fusion for...
While non-specific low back pain (NSLBP) is a common diagnosis, Tim Germon (Derriford Hospital, Plymouth, UK) argues that most low back pain is in fact specific. He speaks about the importance of reaching a diagnosis in order to drive...
A new study has found that after cervical decompression surgery, cervical spondylotic myelopathy (CSM) patients exhibited improved gait pattern, spatiotemporal parameters, spine and lower extremity range of motion (ROM), and patient reported outcomes. The study was carried out by...
Researchers at Johns Hopkins Medicine (Baltimore, USA) report that a computer programme they designed may help surgeons identify and label spinal segments during real time operating room procedures and avoid the costly and potentially debilitating consequences of operating on...
The US Food and Drug Administration (FDA) has approved the M6-C artificial cervical disc (Orthofix Medical) for patients suffering from cervical disc degeneration. The artificial disc was developed by Spinal Kinetics, a company acquired by Orthofix in April 2018. The...
Southern New Hampshire Medical Center has installed the 7D Surgical System for spinal procedures. This system virtually replaces standard fluoroscopy, providing the surgical team with a fast, accurate and radiation-free tool for the placement of spinal implants. The 7D Surgical System...
Sirakoss has been granted CE mark clearance in the European Union (EU) for Osteo3, a novel nanosynthetic bone graft substitute designed to improve patient healing, offering surgeons a more advanced solution for repairing bone fractures. Based on proprietary nanoporous technology,...
Three new StabiLink Dual Lamina Implants (Southern Spine) have been released.  Alan H Daniels, associate professor of Orthopaedic Surgery at The Warren Alpert Medical School of Brown University (Providence, USA) has specifically used the StabiLink Dual Lamina constructs as...
A novel enhanced recovery after surgery (ERAS) protocol developed by Penn Medicine (Philadelphia, USA) for patients undergoing spinal and peripheral nerve surgery significantly reduced opioid use. A new study published in the Journal of Neurosurgery: Spine showed that when an ERAS protocol was...
The editors-in-chief of major cardiovascular journals—of both US and European societies—have come together to “sound the alarm” about the dangers of medical misinformation that has been disseminated through the internet, social media, and other platforms. They claim that this...
The Secure-C cervical artificial disc (Globus Medical) is now covered by Anthem, one of the largest health benefits companies in the United States with close to 40 million medical members and over 73 million lives covered. Secure-C is designed for...
A new patent has been issued by the United States Patent and Trademark Office (USPTO) for United States Patent No. 10,143,501 entitled “Expandable Interspinous Device”. This new patent relates to Aurora Spine’s family of minimally invasive spinal implants, bolstering...
The first US patients have been treated with the Mazor X Stealth Edition (Medtronic) for spine surgery following its commercial launch. The technology offers a procedural solution for surgical planning, workflow, execution and confirmation. The system was first used...
Daniel Spencer is a business manager at Charlton Morris, an executive search firm specialising in orthopaedics, spine and simulation. He argues that while adoption of virtual reality and simulation represents a “leap of faith” for hospitals, the technology has...
  Bioventus has launched OSTEOMATRIX+, a biphasic bone graft for use in bone remodelling in a variety of orthopaedic and spine applications. OSTEOMATRIX+ is a mouldable bone graft substitute consisting of bovine collagen and biphasic, hydroxyapatite/ß-tricalcium phosphate granules designed to produce a porous scaffold...
Back pain app creator, Kaia Health, today announces it has raised US$10 million in a Series A round led by Balderton Capital. The investment will be used to support Kaia Health’s US rollout, including a new office in New...
The US government shutdown means the country’s Food and Drug Administration (FDA) cannot accept new user fees, which means the agency cannot accept new medical product applications. FDA commissioner Scott Gottlieb took to Twitter to highlight agency employees who are...
Mighty Oak Medical has received CE mark clearance for its patient-specific, 3D-printed FIREFLY pedicle screw navigation system, extending its use into the European market. The technology is already available in Australia and New Zealand, and has been approved for...
Aakash Agarwal (Department of Bioengineering and Orthopaedic Surgery, Engineering Center for Orthopaedic Research Excellence, University of Toledo, Toledo, USA) has filed an official citizen petition to the US Food and Drug Administration (FDA) calling for a ban on the...
New results suggest that patients treated with chronic opioids prior to spine surgery are “significantly less likely” to achieve meaningful improvements at one-year in pain function and quality of life; and less likely to be satisfied at one-year with...
Researchers at the University of Toronto (Toronto, Canada) have released “exciting” proof-of-concept data that genetically-engineered SMaRT cells can degrade CSPGs in vitro and that human neural stem cell (NSC) grafts can form long axonal processes in the chronic cervical...
For the first time, researchers at University of California San Diego School of Medicine and Institute of Engineering in Medicine (La Jolla, USA) have used rapid 3D printing technologies to create a spinal cord, then successfully implanted that scaffolding,...
A successful first-in-human surgical procedure utilising ARAI, an augmented reality and artificial intelligence based surgical navigation system (HoloSurgical) has been carried out. The ARAI is an advanced digital surgery platform that combines 3D visualisation, data analytics, and machine learning to...
Ulrich medical USA has announced the market entry of a vertebral body replacement device which is the company's flagship technology in the US spine implant market. The Solidity Vertebral Body Replacement (VBR) device recently received FDA clearance and the world's first implantation of...
The Japanese Ministry of Health, Labor and Welfare has granted a marketing authorisation for EVENITY (romosozumab; Amgen and UCB) for the treatment of osteoporosis in patients at high risk of fracture. Amgen and UCB are co-developing EVENITY worldwide, with development...
SpineSource has acquired the intellectual property assets of two spinal implant systems from Kisco International (France). The acquisition includes the L-VARLOCK expandable lumbar cage which SpineSource has marketed, sold and distributed in the United States since 2016. The acquisition also...
It was announced at the JPMorgan Healthcare Conference (7–10 January, San Francisco, USA) that SpinalCyte has been issued a new Australian patent related to its fibroblast technology. The company’s portfolio in spine treatments now includes 36 US and foreign patents...
It has been announced that IDCT (DiscGenics) has passed the initial planned safety review of its Phase I/II trial evaluating the allogeneic, injectable disc cell therapy in patients with mild to moderate degenerative disc disease (DDD). In this first planned...
NuVasive today announced a new organisational structure and associated executive team that chief executive officer J Christopher Barry has selected. Barry joined the company as CEO on 5 November, 2018. As part of the new organisational structure, NuVasive announced the following...
Spineway, in collaboration with its Peruvian distributor, presented its operating techniques to some one hundred local surgeons during a recent symposium in Peru. Established in Peru since 2014 thanks to the leading distributor in orthopaedic surgery and neurosurgery, Spineway decided...
The Society for Brain Mapping and Therapeutics (SBMT) and the Brain Mapping Foundation (BMF) recently hosted their 5th Annual Neuroscience-20 event in Buenos Aires, Argentina (N20; 26–27 November). For the past five years the goal has been to get...
Swedish digital healthcare provider, Min Doktor, and Kaia Health, a digital therapeutics company, have partnered to offer back pain treatment through a mobile application. A recent study found that Kaia Health’s artificial intelligence (AI) app reduced user-reported back pain...
Medtronic today announced it has completed the acquisition of Mazor Robotics. The total value of the transaction is reported at US$1.7 billion, or US$1.3 billion net of Medtronic's existing stake in Mazor and cash acquired. Under the terms of the acquisition...
The RESPONSE 4.5/5.0mm System (OrthoPediatrics) has been launched in the USA. The company’s newest system, which received US Food and Drug Administration (FDA) 510(k) clearance in October, represents a product expansion for physicians to treat complex scoliosis in smaller...

ExcelsiusGPS launched in Europe

The ExcelsiusGPS robotic guidance and navigation system (Globus Medical) has been installed in several hospitals across Europe. The system won CE Mark clearance in the EU in early 2017 with indications for use in both minimally invasive and open procedures for orthopaedics...
The Monolith corpectomy system (NuVasive) has been granted expanded FDA 510(k) clearance. The system is now cleared for procedures in the cervical spine, between the C3-C7 vertebral bodies, to treat diseased or damaged vertebral body caused by fractures, tumours, osteomyelitis...
The Japanese Pharmaceuticals and Medical Devices Agency (PMDA) has approved a Clinical Trial Notification (CTN) application for IDCT (DiscGenics), an allogenic injectable disc cell therapy for the treatment of degenerative disc disease (DDD). IDCT is available off-the-shelf and offers a...
A Select Health of South Carolina clinical policy, dated 1 September, 2018, has been issued for the exclusive coverage of the coflex interlaminar stabilisation device (Paradigm Spine) for the treatment of lumbar spinal stenosis in patients meeting certain eligibility...
Based on its recent analysis of the North America spinal fusion device performance enhancers market, Frost & Sullivan recognises Vallum with the 2018 North America New Product Innovation Award for its interbody spinal fusion device, PEEKplus. “To enable bioactivity and initiate...
The successful start of a first in human clinical study for the zLOCK spinal facet joint fixation system (ZygoFix) has been announced. The clinical study comprised several procedures to date and a six-month follow-up of the first case. The first...
At the 2018 annual meeting of the German Spine Society (DWG; 6—8 December, Wiesbaden, Germany), joimax will be introducing its Endoscopic Generation 4 Devices and showcasing new 3D-printed titanium implants. This year, joimax will be focusing on their Endoscopic Tower Generation...
Bob Paulson and Phil Soran have been appointed to Spineology’s board of directors. Phil Soran is an entrepreneur who has founded several technology companies and was inducted into the Minnesota Business Hall of Fame in 2016. He was co-founder, president,...
FDA 510(k) clearance has been granted for the SAXXONY posterior cervical thoracic system (Nexxt Spine). The system is designed to stabilise cervical (C1 to C7) and thoracic (T1 to T3) spinal segments via posterior screw fixation in patients with...
It has been announced that Mainstay Medical will participate in the upcoming 13th German Spine Congress of the Deutsche Wirbelsäulengesellschaft (DWG; 6—8 December, Wiesbaden, Germany). DWG will be the first medical meeting at which pivotal clinical data from the...
A recent study found that using a minimally invasive technique (MIS) for the placement of pedicle screws at the upper instrumented vertebra lowered the incidence of proximal junctional kyphosis (PJK) and revision surgery for PJK at two years. The...
The US Food and Drug Administration (FDA) Bone, Reproductive and Urologic Drugs Advisory Committee (BRUDAC) are to review data supporting the Biologics License Application (BLA) for Evenity (romosozumab) (Amgen and UCB) for the treatment of osteoporosis in postmenopausal women at...
FDA 510(k) clearance has been granted for the Olympic minimally invasive surgery (MIS) posterior spinal fixation system (Astura Medical). The Olympic MIS system delivers a new level of intraoperative flexibility and efficiency by allowing surgeons to customise to their preferred...
A partnership has been announced between FundamentalVR and University College London Hospitals NHS Foundation Trust (UCLH). Two surgical simulators have been installed at UCLH’s flagship University College Hospital (London, UK). UCLH the first in Europe to have adopted the VR...
The FDA has cleared SpinalCyte’s Investigational New Drug (IND) protocol for CybroCell. This is considered to be the first IND approval for a fibroblast cell therapy in a chronic condition outside of dermatological uses. The clearance allows SpinalCyte to begin...
The US FDA has announced plans to modernise its 510(k) clearance programme for approving medical devices for the US market. Data show that about 20% of current 510(k) devices are approved on trials that compare novel devices to predicate...
The first US clinical human use of the Voyant system (Viseon) for minimally invasive spine surgery access, illumination and visualisation has been announced. The case was performed by neurosurgeon John J. Knightly of the Atlantic NeuroSurgical Specialists in Morristown,...
An AmeriHealth Caritas Clinical Policy, dated 1 September, 2018, has been issued for the exclusive coverage of the coflex interlaminar stabilisation device (Paradigm Spine) for the treatment of lumbar spinal stenosis. Lumbar spinal stenosis (LSS) affects 1.6 million patients annually and...
Zimmer Biomet recalled 1,360 spinal fusion and long bone stimulators due to a lack of adequate validation and controls to ensure product cleanliness. The FDA has identified this as a Class I recall, making it the most serious type...
CT-guided pulsed radiofrequency is safe and effective in people with acute lower back pain that have not responded to conservative treatment, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA; 25–30...
At this year's annual meeting of the Radiological Society of North America (RSNA; 25-30 November, Chicago, USA), Ziehm Imaging presents a range of mobile C-arms to provide suitable options for surgeons’ different individual demands. Their Vision RFD 3D and...

Donna Ohnmeiss

A self-described “long-shot” and in the first generation of her family to attend university, Donna Ohnmeiss speaks to Spinal News International about why she chose to put her degree in mathematics to use in clinical research, and how her work on...
As emerging and existing technologies continue to shape the way we communicate and spread knowledge, the potentials of digital learning is given increasing consideration. At the recent Eurospine 2018 annual meeting (19–21 September, Barcelona, Spain), the importance of remote...
“Dear Distinguished Professor, we invite you to submit...” Christopher M Bono warns of the rise in predatory publishing, drawing on his own experiences of falling for a well-worded scam email. As editor-in-chief of the North American Spine Society’s flagship...
Statera Spine has announced the formation of the company as a subsidiary of Ortho Kinematics. Statera will leverage the operational backbone and technology platform developed by Ortho Kinematics, but will focus on the commercialisation of Profile-ESP. Profile-ESP is an analytics...
A recent study has reported significant improvements in patients’ frailty status at one-year after surgery, as shown by the cervical deformity frailty index (CD-FI). The data, including a discussion about the efficacy of the index tool itself, were presented...
Costs were found to decrease for implants in surgery when prices were known, concludes a study presented by Andrew Glennie from Dalhousie University, Halifax, Canada, at the Eurospine 2018 annual meeting (19–21 September, Barcelona, Spain). “Suffice to say there is quite a...
Paul Arnold, a spine surgeon based in Kansas for most of his career, now practising at the University of Illinois, USA, and current chair of the ethics and professionalism committee of the North American Spine Society (NASS), talks to...
  EOS imaging have announced the first two installations in Barcelona, Spain at Clavel's Instituto, a spine centre of Hospital Quiron, and the HM Delfos Hospital. In addition, the first installation in Portugal is planned in Lisbon by the end...
Mazor Robotics has announced that at a Special General Meeting of Shareholders held on 19 November, 2018, Mazor shareholders approved the previously announced definitive merger agreement with wholly-owned subsidiaries of Medtronic. Approximately 53% of Mazor Robotics ordinary shares were represented...
SurGenTec has announced the successful completion of the initial clinical launch of its new GraftGun bone graft delivery system combined with ViBone Viable Bone Matrix prefilled tubes. This early evaluation of the combined products was focused in the Minimally Invasive...
Highlights: Costs curbing the rise of robotics in spinal surgery Augmented reality surgical navigation technology enables high accuracy pedicle screw placement Eurospine audience sceptical of digital learning's potential in spinal surgery training Scoliosis Research Society president Todd Albert’s half-day...
This advertorial has been sponsored by INVIBIO™ Jill Wright Donaldson, MD, is a neurosurgeon at Community Hospital North (Indianapolis, IN, USA), specialising in the surgical management of complex spine disorders, neoplasms of the brain and spine, and peripheral nerve entrapment....
Medicrea has announced that the 3,000th surgery utilising Medicrea’s patient-specific UNiD ASI technology has been successfully completed. Five years after its initial launch, over 3,000 patients worldwide have benefitted from UNiD ASI, the 100% proprietary, pre-operative planning technologies and services...
  Vertiflex has announced additional results from a randomised, controlled trial of its Superion Indirect Decompression System in patients with lumbar spinal stenosis (LSS). The results, published in the Journal of Pain Research, showed an 85% decrease in the proportion of...
  Zimmer Biomet has announced that the US Food and Drug Administration (FDA) has approved an extension to the Mobi-C Cervical Disc labelling to include seven-year clinical results. The updated data remain consistent with the previous findings at two and...
Altus Capital Partners today announced it has acquired ChoiceSpine. Financial terms of the transaction were not disclosed. ChoiceSpine and Knox Spine (collectively, the Company) collaborates with physicians to develop new products which incorporate current medical technology with customised patient solutions....
Baptist Medical Park Surgery Centre, an ASC facility in Pensacola, Florida, USA, announced that it has successfully completed their first SI Fusion procedure with the recently purchased Mazor Robotics Renaissance system.  “The acquisition of the Mazor Robotics Renaissance system...
RTI Surgical has announced that HealthPartners, the largest consumer governed non-profit healthcare organisation in the USA, issued a positive coverage decision for minimally invasive sacroiliac (SI) joint fusion surgery, effective 1 November, 2018. This decision expands access to RTI’s SImmetry System...
  Implanet has announced the award of CE marking for the Jazz Cap System, developed to meet the constraints of vertebral fusion indications in adults. Jazz Cap System, which was developed principally to facilitate the treatment of degenerative conditions in adult...
Level 1 evidence, presented at EUROSPINE 2018 in Barcelona, Spain, demonstrates that i-FACTOR peptide enhanced bone graft results in significantly higher rates of fusion in uninstrumented lumbar spinal surgery than does the use of allograft. Michael Jacobsen (Middelfart, Denmark) spoke...
  The "Orthopaedic devices market size, share and trends analysis report by application (hip, knee, spine, cranio-maxillofacial, dental, SET), by product (accessories, surgical devices), and segment forecasts, 2018 - 2026" report has been added to ResearchAndMarkets.com's offering. The global orthopaedic device market size is expected...
Aurora Spine has announced that it has acquired an exclusive licence to US patent number 9,451,986 titled “Percutaneous sacroiliac joint implant and method for surgically inserting and securing the implant into the sacroiliac joint” in an agreement with SILIF...
Biogen was announced as the winner of the Orphan Product Award at last night’s UK Prix Galien 2018, for Spinraza, which in 2017 became the first and only approved treatment for 5q spinal muscular atrophy (SMA). In addition, the...
Colin Haines and Christopher Good, spine surgeons at Virginia Spine Institute, Virginia, USA, have performed the world’s first spinal surgery using combined endoscopic and robot-guided technology. The inaugural procedure was conceived by this team of experts out of a...
NuVasive has announced the US commercial launch of Brigade Lateral, the industry's first interbody implant and instrumentation optimised for lateral anterior lumbar interbody fusion (ALIF) spine surgery. NuVasive's Lateral ALIF is a proprietary spine procedure enabling access to L5-S1 from...
K2M

Stryker closes US$1.4B K2M buy

Stryker has closed its US$1.4 billion acquisition of K2M. With the acquisition, K2M will become a wholly owned subsidiary of Stryker, the companies said. Stryker paid US$27.50 per share for each outstanding share of K2M, representing a 27% premium over K2M’s average closing...
Life Spine has announced the initiation of the PROLIFT Expandable clinical study with Ahmed Khan, Central Connecticut Neurosurgery and Spine, Connecticut, USA. Mariusz Knap, vice president of Marketing and Business Development notes, “Clinical studies are the foundation for advancing innovative spine...
SpinalCyte has announced that a single injection of modified human dermal fibroblasts (HDFs) resulted in significant improvements of disc height and pain reduction 12 months after injection of the cell therapy for patients with degenerative disc disease (DDD). The trial...
Simplify Medical, maker of the Simplify cervical artificial disc, has announced that it has completed the enrolment and treatment of all patients in its US Investigational Device Exemption (IDE) pivotal trial evaluating the Simplify Disc for two-level cervical disc replacement. The...
Backpack Health’s cloud-based mobile app offers paediatric scoliosis patients and their caregivers a centralised platform to manage health data and connect with the global scoliosis community. Backpack Health and the Children’s Scoliosis Foundation (CSF) have announced a partnership that will...
Innovent Biologics, a biopharmaceutical company, has announced that the National Medical Products Administration (NMPA, successor to the CFDA) has accepted its new drug application (NDA) for adalimumab biosimilar candidate (IBI303). IBI303 is a recombinant human anti-TNF-α monoclonal antibody independently developed...
Bio2 Technologies, a privately held orthopaedics company, has announced that it received US Food and Drug Administration (FDA) approval to begin enrolment in an IDE clinical study to evaluate Vitrium as a cervical interbody fusion device. Vitrium will be evaluated...
EOS imaging has announced the change of its leadership effective 1 January 2019. The Board of Directors, in agreement with Marie Meynadier, chief executive officer of EOS imaging, has decided to change the leadership of the company to strengthen...
The era of routine robotic-assisted spinal surgery is on the horizon. Despite the hype, however, there remains little market penetration, with affordability and the degree of value-added by such technology representing significant barriers to complete disruption of standard practice. In a recent...
RTI Surgical and Paradigm Spine have entered into a definitive agreement whereby RTI will acquire all outstanding equity interest of Paradigm Spine in a cash and stock transaction valued at up to US$300 million, consisting of US$150 million at closing plus...
A recent study found no improvements in pedicle screw accuracy but increased radiation using intraoperative computed tomography (CT)-based navigation compared to a freehand technique in idiopathic scoliosis surgery. The study was carried out by Wiktor Urbanski (Wroclaw University, Wroclaw,...
NuVasive has announced it has received 510(k) clearance from the US Food and Drug Administration (FDA) for use of its COHERE Porous PEEK implant in eXtreme Lateral Interbody Fusion (XLIF) surgical spine procedures. NuVasive's patented Porous PEEK technology offers three-dimensional...
SpinalCyte, a regenerative medicine company focused on regrowth of the spinal disc using Human Dermal Fibroblasts (HDFs), has announced the issuance of new patents in Hong Kong and Europe. The company’s intellectual property in spine treatments now includes 35...
Spinal Elements has recently announced FDA clearance for claims related to the macro-, micro-, and nano-surface structure of its Ti-Bond surface coating technology. Utilising this advancement, the company have recently introduced the Lucent XP height- and lordosis- expandable interbody device. Interbody...
Titan Spine, a medical device surface technology company focused on developing surface-enhanced spinal interbody fusion implants, has announced it has closed a substantial round of Series B financing with its current investment partner, Southlake Equity Group. Titan will use...
Dedicated surgical teams have been found to reduce surgical times and room times in patients with adolescent idiopathic scoliosis (AIS). Surgical times decreased by 13%, and room times by 11%, in 590 cases of AIS between 2006 and 2015....
Speaking anonymously to Spinal News International, a career and life coach for physicians said that the most effective way to address the issue of physician burnout, in his experience, is “experimental learning during the course of a three- to...
A recent study has concluded that the clinical benefits of a minimally invasive surgical technique appear to “diminish” as a function of fusion length. The data, which examined the relationship between open versus minimally invasive lumbar fusion and the...
With the introduction of new wearables designed for intraoperative use, such as the Hololens (Microsoft) head-up display, there has been considerable interest in bringing augmented reality to surgical procedures in recent years. At the North American Spine Society (NASS) annual...
TETRAfuse 3D technology (RTI Surgical) won a 2018 spine technology award from Orthopedics This Week. RTI Surgical accepted the award at the North American Spine Society’s (NASS) 33rd annual meeting (26–29 September, Los Angeles, USA). “RTI is honoured to receive this important...
NuVasive have announced it has entered into a strategic partnership with Biedermann Technologies, a company that holds a broad and extensive patent and technology portfolio in the fields of spinal and extremity surgery, based in Donaueschingen, Germany. Biedermann Technologies works...
  Research that highlights a worrying trend between cycling and spinal trauma has recently been published in The Surgeon. Although the authors of the paper, M P Broe (Mater Misericordiae University Hospital, Dublin, Ireland) and colleagues, state that, “It is...
Rates of survival are higher, and respiratory intervention rates are lower, in 25 infants with presymptomatic 5q spinal muscular atrophy (SMA) treated with Spinraza (nusinersen). Biogen announced these new interim results from their NURTURE trial; this is an ongoing...
Medtronic has announced the US launch of the Infinity Occipitocervical-Upper Thoracic (OCT) System designed to simplify posterior cervical spine surgery. A company press release describes the Infinity OCT System as a procedural solution that integrates navigation and biologics with...
The Ennovate® PentaCore® Screw is the new benchmark in the Pedicle Screw Systems market. Ennovate screws have a significantly higher pullout force, shear strength, and overall endurance than other screws currently available on the market, concludes a recently published study...
The global spinal implants market is forecast to grow at a 7% compound annual growth rate to exceed US$19.5 billion by 2024, according to a recent Market Research Engine report. The growth of bioresorbable implants is expected to propel the spinal implants...
Medtronic and Mazor Robotics have announced that the two companies have entered into a definitive merger agreement under which Medtronic will acquire all outstanding ordinary shares of Mazor for US$58.50 per American Depository Share, or US$29.25 (104.80 ILS) per...
ImmersiveTouch, a Chicago-based company, announced the launch of ImmersiveView, the only suite of integrated virtual reality real-time solutions for personalised surgical planning, patient engagement, and surgical training using patented haptic technology. ImmersiveView was launched at the North American Spine...
 Philip Sell (Leicester and Nottingham, UK) tells Spinal News International that as the field of spine surgery evolves from using generic to more specific outcome measures, he would be delighted to see a move away from surrogate outcome measures...
 Factors characterising an indication for surgery in lumbar spinal stenosis Outcomes following surgery for spinal stenosis present great variability, suggesting that patient selection could be improved. Anne Mannion (Senior Research Fellow, Spine Centre, Schulthess Klinik, Zürich, Switzerland) tells Spinal News...
 “Outcomes are important for patients. It is very important that we understand what happens to our patients when we carry out treatments, be they surgical interventions or conservative treatment. If we do not know that, we cannot adapt our...
 Frank Kandziora (Frankfurt, Germany), the 2018 president of EUROSPINE, the Spine Society of Europe, tells Spinal News International that assuring quality in spine surgery is a cornerstone of patient care.
A recent study reports that new technology utilising augmented reality surgical navigation can be clinically used to place pedicle screws, enabling both high accuracy and an acceptable navigation time. The results were presented by Gustav Burström, Karolinska Institutet, Stockholm,...
Johnson & Johnson Medical Devices Companies have announced that DePuy Synthes is introducing SENTIO MMG, a first-of-its-kind digital mechanomyography platform designed to assess nerve status and identify and avoid peripheral nerves during spine surgery. SENTIO MMG enables motor nerve...
CoreLink have announced the expanded commercial launch for the FLXfit15 articulating-expandable intervertebral body fusion device. FLXfit15 is a posterior lumbar expandable interbody device that offers up to 15 degrees of controlled and continuous expansion and is one of the only...
The Therapeutic Goods Administration (TGA) has granted approval to Nevro for its next-generation Senza II spinal cord stimulation system delivering the company’s proprietary HF10 therapy. According to Nevro, the Senza II system offers the outcomes and clinical advantages of...
Highlights: Surgeons call for ban on pedicle screw reuse and demand two-step asepsis process Second scoliosis surgery of the day as safe and effective as first Many surgeons do not use patient-reported outcome measures in spine care Scoliosis Research...
Johnson & Johnson has announced its acquisition of spinal fusion implant developer Emerging Implant Technologies for an undisclosed amount. Norderstedt, Germany-based EIT produces 3D-printed titanium interbody implants specifically for spinal fusion surgery. The company’s devices use proprietary cellular titanium which...
Benvenue Medical, a developer of minimally invasive expandable implant solutions for lumbar fusion, has announced it has completed the divestiture of its vertebral augmentation systems portfolio for an undisclosed amount to IZI Medical Products. A company press release states...
Contaminated pedicle screws cost hundreds of thousands of US dollars a year, and through an increase in surgical site infections result in additional and avoidable patient morbidity. Anand Agarwal (University of Toledo, Toledo, USA) and colleagues are calling for...
Frank Kandziora

Frank Kandziora

Once an aspiring architect, Frank Kandziora has never looked back from the medical profession since being assigned a medical assistant during his military service in Germany. As the outgoing president of EUROSPINE, he reflects on the successes of the...
Invuity, a medical technology company focused on advanced surgical devices to enable better visualisation, announced that it has entered into a definitive agreement with Stryker, pursuant to which Stryker will acquire all of the outstanding shares of Invuity...
New research outlines how spinal injuries in suicidal jumpers differ from those in non-suicidal patients with regard to patient demographics, mental health condition, injury location, neurological damage and associated injuries. The study was carried out by Hiroki Kano and...
Paradigm Spine, a company specialising in the treatment of lumbar spinal stenosis, has announced the issuance of a broad coverage medical policy from BlueCross BlueShield of South Carolina covering its coflex device for the surgical treatment of lumbar spinal...
Captiva Spine has announced it has received 510(k) clearance from the US Food and Drug Administration (FDA) to market its TirboLOX-L 3D printed Titanium lumbar cages. TirboLOX-L titanium lumbar cages are created using advanced 3D printing technologies to form titanium...
The Spine Center at Dignity Health St. Mary's Medical Center (San Francisco, USA), has been selected to participate in a FDA/IDE pivotal study, sponsored by Premia Spine, studying the use of the Tops System. St. Mary's Medical Center is...
Todd H Lanman is a spine surgeon known for his work on the advancement of total disc replacement surgery and motion preservation. Following his own experiences undergoing a number of spinal surgeries, Lanman has pursued a career dedicated to the restoration of his...
EOS imaging, a 2D/3D imaging company for orthopaedics, has announced the first installation of an EOS system in Mexico, the largest Central American market, at Shriners Hospitals for Children—Mexico, located in Mexico City. “Shriners Hospitals for Children—Mexico, noted for excellent...
UK’s National Institute for Health and Care Excellence (NICE) has published its Appraisal Consultation Document (ACD) outlining a ‘minded no’ for the routine funding of Spinraza (nusinersen) for the treatment of 5q spinal muscular atrophy (SMA) in England, Wales...
Eden Spine’s Sphynx plating system has been granted FDA clearance, the company has announced. Sphynx was designed to complement the company’s Giza titanium vertebral body replacement with rotatable endplates, introduced in 2012. The Giza is intended to replace and fuse a...
SI-Bone has announced that iFuse will be added to the List of Refundable Products and Services in France (Liste des Produits et Prestations Remboursables- LPPR), meaning that the French National Healthcare System will exclusively cover the iFuse procedure. Through...
Todd J Albert is surgeon-in-chief at the Hospital for Special Surgery, New York, USA, and is the current president of the Scoliosis Research Society (SRS). At the 25th International Meeting on Advanced Spine Techniques (IMAST; 11–14 July, Los Angeles,...
NuVasive has announced the Pulse surgical automation platform has received 510(k) clearance from the US Food and Drug Administration (FDA). Pulse is the foundation for the company’s Surgical Intelligence system, and introduces 2D- and 3D-navigation and smart imaging capabilities...
Independence in mobility is the single most important factor affecting quality of life in patients with traumatic spinal cord injury, reports a study in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. Based on validated clinical questionnaires, the study by Julien...
Neuroscientists at UCLA, Harvard University and the Swiss Federal Institute of Technology have identified a three-pronged treatment that triggers axons to regrow after complete spinal cord injury in rodents. In addition to facilitating axon growth through scar tissue, the...
Nusinersen (Biogen) has previously been shown to be effective in the treatment of spinal muscular atrophy in infants under seven months of age; recent research published in Neurology, the medical journal of the American Academy of Neurology, suggests that...
Stryker has announced a definitive merger agreement to acquire all of the issued and outstanding shares of common stock of K2M Group Holdings, a company specialising in minimally invasive spinal devices, for US$27.50 per share, or total equity value...
A novel approach reported by Peter Pijpker and colleagues from the University Medical Center Groningen, Groningen, The Netherlands, outlines the use of 3D virtual planning and 3D-printed models that have the ability to change how complex spinal surgeries are...
At the NSpine meeting (London, UK), Ahmet Alanay (Istanbul, Turkey) discussed the surgical management of deformity in spina bifida patients. You can watch the full talk and subsequent discussion below.
According to Woojin Cho (Montefiore Medical Center, the University Hospital for Albert Einstein College of Medicine, New York, USA), who presented at the 25th International Meeting on Advanced Spine Techniques (IMAST; July 11-14, Los Angeles, USA), spinal surgeons continue to wrongly recommend...
  NuVasive and Siemens Healthineers have announced a strategic partnership, which is to focus on “technology development, marketing and commercial activities to advance clinical outcomes in minimally invasive spine surgery”, according to the two companies. NuVasive is a spine health technology...
Izana Bioscience, a biopharmaceutical company focused on translational medicine, has announced the initiation of a phase II proof-of-concept clinical study of namilumab in ankylosing spondylitis, a debilitating arthritic disease of the spine that affects millions of people worldwide. The randomised,...
Scoliosis correction is an extensive surgery, and operating on multiple patients in one day can be exhausting for the surgical team. However, recent research finds that the second surgery of the day has similar outcomes and complication rates compared...
Following the completion of its first surgical cases, K2M has received Food and Drug Administration (FDA) 510(k) clearance and a CE mark for its Cayman United Plate System. The Cayman United Plate System is designed for rigid fixation to K2M's...
At the NSpine meeting (London, UK), Alessandro Gasbarrini (Bologna, Italy) discussed decision making in recurrent spinal tumours. Click to watch the full talk here.
Connecticut Orthopaedic Specialists have announced the enrollment of the initial patients within Simplify Medical’s clinical trial to evaluate the Simplify Disc, its novel investigational cervical disc, at two adjacent cervical levels. James J Yue, a spine and neck specialist...
Bioventus has entered into a definitive agreement to divest its next generation bone morphogenetic protein (BMP) development programme to a new company formed by Viscogliosi Brothers, a private equity investment firm focused on developing innovative neuromusculoskeletal technologies. Bioventus acquired the...
  The first patients have been enrolled in an investigational device exemption (IDE) clinical trial evaluating the safety and efficacy of the next-generation P-15L peptide enhanced bone graft (Cerapedics) in transforaminal lumbar interbody fusion (TLIF) surgery. Cerapedics gained FDA approval...
A novel immune-evasive gene therapy has restored skilled grasping function in paralysed rats, allowing treated rodents to independently reach for and pick up sugar cubes, research recently published in Brain reports. The findings of the preclinical study support the...
Concorde Lift (DePuy Synthes), a new expandable interbody device, is launching in the USA. The implant is designed to treat patients suffering from degenerative disc disease as part of the new offering called UNLEASH MIS TLIF (Transforaminal Lumbar Interbody...
At the NSpine meeting (London, UK), Bronek Boszczyk (Benedictus Clinic Tutzing, Germany) discussed combined convex and concave costoplasty for posterior chest wall in adolescent idiopathic scoliosis (AIS).
In Lenke type 1 or type 2 adolescent idiopathic scoliosis (AIS), significant correction of the main thoracic curve with relative under-correction of the proximal thoracic curve increases the incidence of postoperative shoulder height imbalance. This is the conclusion presented...
The next evolution of the Reline system (NuVasive) has just launched: the Reline MAS Midline (RMM). The company description says this system provides “procedural versatility in a compact midline construct”. RMM incorporates low-profile modular implants and advanced system instrumentation to...
The US Food and Drug Administration (FDA) has granted approval to market a polyetheretherketone (PEEK) spinal interbody fusion device with a PEEKplus nanotextured surface (Vallum Corporation). The PEEKplus nanotextured surface is the first and only FDA-cleared nanotextured surface on...
Cerapedics has announced that the company completed a US$22 million financing led by KCK Group, a family investment fund that focuses on innovative medical technologies that meet significant clinical needs. This equity funding will accelerate the commercial release of i-FACTOR...
The results of a report looking at the rates of spinopelvic malalignment in nearly 600 patients show that malalignment is common both before and after short-segment degenerative fusions. These findings are detailed in the first peer-reviewed publication from the...
Mainstay Medical International, a medical device company focused on bringing to market ReActiv8, an implantable neurostimulation system to treat chronic low back pain, announces the completion of all implants in ReActiv8-B, its US IDE clinical study. A total of 204...
Spine surgeons earn high ratings for their skill and good clinical outcomes on internet review sites—but are more likely to receive negative ratings and comments on factors pertaining to clinic staff, billing, and wait times, reports a landmark study...
EOS imaging has announced the installation of its EOS system at the University Hospital Center of Grenoble Alps (CHUGA), a state-of-the-art hospital facility for osteoarticular surgery in children and adults. CHUGA is the 20th university hospital centre to acquire an...
HD LifeSciences has received FDA 510(k) clearance for its Hive-C IBFD, a system of interbody devices for anterior cervical fusion procedures. The Hive-C implant system will be commercially available in July 2018. The devices are based on the company’s patented, additive-manufactured Soft Titanium...
South Australian researchers are embarking on a AUD$20 million medical and manufacturing research project which could reduce the chance of infection after orthopaedic surgery, thanks to a little help from the humble dragonfly. Working with leading surgeons and an Australian...
The first surgeries with robotically assisted minimally disruptive placement of the Centerline cortical screw system and the Prolift expandable spacer system (Life Spine) in an ambulatory surgical centre have been announced. “Life Spine is dedicated to address and support minimally...
A recent study, initially published in Nature Communications, shows that anti-oxidation specific epitope (OSE) antibodies protect against osteoporosis, illuminating the potential for a novel approach to treatment. The data presented in the report by Elena Ambrogini (Division of Endocrinology, Department...
The use of i-FACTOR peptide enhanced bone graft (Cerapedics) resulted in a 50% fusion rate, compared to a 20% fusion rate using allograft in patients with non-instrumented surgery. This is the result of the IVANOS study evaluating i-FACTOR peptide...
  Renovis Surgical Technologies has announced that it has received 510(k) clearance from the US Food and Drug Administration (FDA) to market the Tesera SA Hyperlordotic ALIF interbody spinal fusion system. Tesera SA is a porous titanium stand-alone anterior lumbar interbody...
The results of the COAST-W trial demonstrate that Taltz (ixekizumab; Eli Lilly and Company) is a safe and effective treatment for Ankylosing Spondylitis (AS), also known as radiographic axial spondyloarthritis. COAST-W is a Phase 3 trial, and is the...
EOS imaging has announced the installation of an EOS imaging system at ATOS Klinik Heidelberg, establishing it as the first private practice in Germany to offer the low-dose 2D/3D imaging system. The system will be available at the spinal surgery...
As a multidisciplinary membership organization, the North American Spine Society (NASS) has an incredible group of volunteers who work on many initiatives in the research, health policy, education, communications and advocacy arenas. This supplement will provide an update on...
Paediatric patients with severe spinal deformity are at a high risk of revision surgeries. Presenting his research at the Global Spine Congress (GSC; 2–5 May, Singapore), Munish Gupta (Department of Orthopedics, Washington University, St. Louis, USA) reported a 12%...
The A-CIFT SoloFuse HA (SpineFrontier) has received FDA approval. The company states that the A-CIFT SoloFuse HA standalone system was produced “to leverage the familiarity of existing techniques, while providing an alternative to traditional plating for one level procedures—with the...
The annual census of UK consultants and higher speciality trainees—Focus on Physicians 2017–18—indicates that more than half of all consultants and two thirds of trainees reported frequent gaps in trainees’ rotas, with one in five respondents saying these are...
Back Pain Centers of America, a call centre which connects people searching for solutions to their neck and back pain with spine specialists, have released a spine health e-book entitled Critical Factors for Successful Spine Surgery. This 65-page free...
US spine care providers have a brand new tool to measure and improve patient care: a diagnosis-based clinical data registry that tracks patient care and outcomes.  Launched by the North American Spine Society (NASS), this web-based platform will allow...
The US Food and Drug Administration (FDA) have granted clearance for the Catamaran sacroiliac joint fixation system (Tenon Medical) specifically indicated for sacroiliac joint fusion for conditions including sacroiliac joint disruptions and degenerative sacroilitis. The Catamaran sacroiliac joint fixation system...
The US Food and Drug Administration (FDA) has granted 510(k) clearance of Kyphon HV-R bone cement (Medtronic) for fixation of pathological fractures of the sacral vertebral body (or ala) using sacral vertebroplasty or sacroplasty. Medtronic state that this broadens the...
Porous polyetheretherketone (PEEK) technology (NuVasive) is a clinically viable alternative for improving osseointegration and fusion rates of interbody implants to treat degenerative cervical disc disease, a recent paper in the Journal of Spine & Neurosurgery reports. In the study, 50...
“Decompression and fusion for degenerative spondylolisthesis is associated with reduced risk of opioid dependency”, says Mayur Sharma (Department of Neurosurgery, University of Louisville, Louisville, USA), summarising his latest research, recently published in the Journal of Neurosurgery: Spine. The study...
TriStar Centennial Medical Center (Nashville, USA) is the first healthcare system to incorporate the Levó head positioning system (Mizuho OSI) into their operating room. Mizuho OSI state claim that the system confers better control and safety of a patient’s...
EOS imaging, a 2D/3D imaging and data solutions for orthopaedics, announced the launch of EOSone, its new private practice programme, at Becker’s 16th Annual Future of Spine + The Spine, Orthopedic and Pain Management Driven ASC Conference (14–16 June,...
The latest line of icotec interbody cages, designed to optimise bony integration and post-operative visualisation, has received US Food and Drug Administration (FDA) 510(k) clearance. The clearance includes cages for a variety of surgical approaches, such as cervical fusion...
Almost one third of spine surgeons do not routinely use patient-reported outcome measures (PROMs). This was the result presented by Asdrubal Falavigna (Department of Neurosurgery, Caxias do Sul University, Caxias do Sul, Brazil) at the Global Spine Congress...
A preliminary study has demonstrated the feasibility of using a novel visualisation approach as a valuable adjunct tool for minimally invasive percutaneous procedures. This is the conclusion of Gerard Deib (Division of Interventional Neuroradiology, The Johns Hopkins Hospital, Baltimore,...
The use of a hydrogel after spinal cord injury is responsible for the restoration of independent breathing control in rats, according to research recently published in The Journal of Neuroscience. Researchers at Jefferson, Angelo Lepore (Department of Neuroscience, Philadelphia University and Thomas...
The commercial launch of Fortilink-TS and –L IBF systems (RTI Surgical) with TETRAfuse 3D technology has added to a growing series of interbody fusion devices featuring RTI Surgical’s proprietary TETRAfuse 3D technology. The Fortilink-TS and -L systems are intended for...
Three factors were found to be predictive of survival in a surgical series of metastatic epidural spinal cord compression, including the type of primary tumor and a lower degree of physical disability on the SF-36 physical component score. These...
Patients who take prescription opioids for a longer period before spinal surgery are more likely to continue opioid use several months after surgery, reports a study in The Journal of Bone & Joint Surgery.  According to the new research, led by Andrew...
Amgen has announced that the European Commission (EC) has approved a new indication for Prolia (denosumab) for the treatment of bone loss associated with long-term systemic glucocorticoid therapy in adult patients at increased risk of fracture. The EC approval is based on...
CoreLink, a manufacturer of spinal implant systems, acquired Israel-based Expanding Orthopedics, a privately held medical device developer. Along with the FDA cleared expanding and articulating FLXfit and FLXfit 15 titanium TLIF interbody systems, CoreLink has also acquired a broad array...
According to a study published in BMJ Open, just over half of patients think what a doctor wears is important and more than a third claim that their doctor’s attire influences the satisfaction they have with the care that...
The North American Spine Society (NASS) has issued a coverage policy recommendation for Lumbar Interlaminar Device without Fusion and with Decompression, which applies to Paradigm Spine’s coflex device. This recommendation is particularly significant for coflex because it provides the...
The global spine surgery products market is expected to reach US$16.7 billion by 2025, up from US$10.2 billion in 2016, a Transparency Market Research report states. The report anticipates that the spine surgery products market will grow at a...
The US Food and Drug Administration (FDA) has granted pre-market supplemental approval (PMA) for the coflex interlaminar stabilisation disposable instrument kit (Paradigm Spine). This marks the first approved disposable instrument set for a Class III spinal device to receive...
CIMZIA (certolizumab pegol) is the first therapy to demonstrate positive results in a 52-week, placebo controlled non-radiographic axial spondyloarthritis study. The positive topline results from C-AXSPAND, a Phase 3 multi-centre, randomised, double-blind, parallel-group placebo controlled study to investigate the...
Countries in the European Union have long been the first to receive new innovations in medical technology, as the EU’s Medical Device Directive (MDD) provided quicker routes to implementation of new devices than its equivalent in the USA, the...
An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function, new research published in The Journal of Clinical Investigation suggests.  Researchers at The...
The Rampart One Standard anterior lumbar interbody fusion (ALIF) device (Spineology) has been granted FDA clearance, allowing it to be used with or without supplemental fixation. The Rampart One ALIF interbody fusion system is an anatomy-conserving technology, a press release...
The US Food and Drug Administration (FDA) has granted 510(k) clearance for both the ALTA ACDF interbody spacers (Astura Medical) and HALF DOME lumbar interbody spacers in PEEK-OPTIMA Hydroxyapatite Enhanced (Invibio Biomaterial Solutions). PEEK-OPTIMA HA Enhanced provides an innovative biomaterial...
The use of a bone-anchored anular closure device following discectomy is superior to treating high-risk patients with discectomy alone, a two-year study recently published in The Spine Journal reports. The landmark, randomised superiority clinical trial investigated the Barricaid anular...
The US Food and Drug Administration (FDA) has given 510(k) clearance to Camber Spine to market its ENZA-A titanium anterior lumbar interbody fusion (ALIF) system, a unique, minimally invasive interbody fusion device providing integrated fixation. ENZA-A Titanium ALIF is an...
The committee for medicinal products for human use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion in the marketing authorisation of Prolia (denosumab) for the treatment of bone loss associated with long-term systemic glucocorticoid therapy...
Intraspinal injections of human spinal cord-derived neural stem cells are well tolerated in a Phase I study of four patients with thoracic (T2–T12) ASIA-A grade spinal cord injury. This was the result recently published in Cell Stem Cell, supporting...
Researchers at Hospital for Special Surgery (New York, USA) have launched a pilot study to see how a rheumatologic agent that treats several related autoimmune disorders affects the skeleton. The two-year study, led by Susan M Goodman (Hospital for Spinal Surgery, New...
A Loyola Medicine study has found that 15.4% of patients who take drug holidays from osteoporosis drugs called bisphosphonates experienced bone fractures. During a six-year follow-up period, the yearly incidence of fractures ranged from 3.7% to 9.9%, with the most fractures...
Case performed by Oded Hershkovich and Bronek Boszczyk (both Centre for Spinal Studies and Surgery, Queen’s Medical Centre, Nottingham, UK). nspine Introduction We would like to present an interesting clinical case of adolescent idiopathic scoliosis (AIS), in which the concave costoplasty...
The world’s first advanced robotic treatment device that has been evidenced to improve a patient’s ability to walk is being made commercially available in the USA. Individuals with spinal cord injuries can now access FDA-cleared HAL, which is short...
Massachusetts General Hospital surgeons have proposed the development of a screening measurement to determine the likelihood of prospective National Football League (NFL) players suffering a potentially career-ending degree of cervical stenosis. This research was presented by Mark Callanan (Massachusetts General Hospital...
Spinal stimulation increases the odds of pain relief more than medical therapy when patients are faced with intractable spine or limb pain. This is the result of a recent study, presented in a scientific poster at the American Academy...
Spinal anaesthesia is safe for high-risk patients undergoing lumbar spinal surgery, and allows for better perioperative hemodynamic stability compared to general anesthesia, a recent study published in the Journal of Clinical Anesthesia reports. The study, by Michael Finsterwald (Department of Orthopedic Surgery, Balgrist...
A preliminary study suggests that an investigational drug may help increase protein levels in infants with spinal muscular atrophy. The results of the open label study were presented at the American Academy of Neurology’s 70th Annual Meeting (21–27 April, Los Angeles, USA). Spinal muscular atrophy...
Patients who have been taking opioids as pain relievers for several months before spinal fusion surgery are at increased risk of complications after their surgery, reports a study in Spine. The results were presented at the 18th annual conference...
Surgeons’ procedural choices and patient malalignment are the strongest predictors of distal junctional kyphosis in the first year following surgery. This was the conclusion presented by Peter Passias (Department of Orthopaedic Surgery, NYU Langone Orthopedic Hospital, New York, USA)...
Percutaneous endoscopic lumbar discectomy via an interlaminar approach is effective for lumbar disc herniation, with few complications, reported Jiancheng Zeng (West China Hospital, Sichuan University, Department of Orthopaedics, Chengdu, China), speaking at the 18th annual conference of the International...
Martin Underwood (Warwick Medical School, University of Warwick, Coventry, UK) has worked as a general practioner in Lusaka, Manchester, London and Coventry, UK. He has a track record of community based research into the improved diagnosis and management of musculoskeletal disorders, particularly back...

Raja Rampersaud

An advocate for interprofessional models of care for spine and musculoskeletal disorders, Raja Rampersaud is a spine surgeon globally recognised as a leader and innovator in the minimally invasive field. His clinical research focuses on health services and quality of...
Postoperative gait disturbance significantly increases with age, persisting in elderly patients for longer than in non-elderly patients. This is the finding of a recent study comparing clinical and radiographic outcomes between elderly and non-elderly patients with cervical spondylotic myelopathy undergoing laminoplasty. The...
EOS imaging has announced that University Orthopedics in Providence, Rhode Island, and the Hey Clinic for Scoliosis and Spine Surgery in Raleigh, North Carolina (both USA) have installed the EOS system for low-dose, 2D and 3D imaging of patients. Both...
Both bracing and exercise have demonstrable, significant treatment effectiveness for patients with adolescent idiopathic scoliosis. This was the finding of a randomised, controlled trial presenting level one evidence, carried out by Yu Zheng (Interdisciplinary Division of Biomedical Engineering, The...
The US Food and Drug Administration (FDA) has given 510(k) clearance for the Zyston strut open titanium interbody spacer system (Zimmer Biomet). This marks Zimmer Biomet’s first titanium spinal implant manufactured via a 3D printing process. The Zyston strut open...
Both free hand and robotic-guided S2 alar-iliac (S2AI) screw placement prove to be safe, accurate and reliable techniques for achieving spinopelvic fixation. This is the finding of Jamal Shillingford (Department of Orthopaedic Surgery, Columbia University Medical Center, The Spine...
The international Society on Scoliosis Orthopaedic Rehabilitation and Treatment (SOSORT) elected Luke Stikeleather as president at its annual meeting held this spring in Dubrovnik, Croatia. Stikeleather is the founder and president of the National Scoliosis Center located in Fairfax (USA). SOSORT...
The US Food and Drug Administration (FDA) has given 510(k) clearance to the PRO-LINK titanium stand-alone cervical spacer system (Life Spine) for spinal fusions. PRO-LINK feature’s Life Spine’s OSSEO-LOC surface treatment, and has experienced great success since inception, a press...
A novel endoscopic, stand-alone transforaminal decompression and fusion (TLIF) technique using the VariLift-LX system (Wenzel Spine) has been described in a 24 consecutive patient case series, published in the Journal of Spine. The VariLift-LX system is a stand-alone, threaded expandable...
Prominent spinal neurosurgeon Todd H Lanman (Lanman Spinal Neurosurgery, Los Angeles, USA) has been honored by the Los Angeles Business Journal as one of its 2018 ‘Leaders in Health Care,’ taking home the prestigious award at the 2018 Health...
Using stem cell derived neuronal cells reprogrammed from genetically identical animals eliminated the need for immunosuppression measures. A major hurdle to using neural stem cells derived from genetically different donors to replace damaged or destroyed tissues, such as in a...
Bruce Dall is a spine surgeon, having gained his medical qualification at the University of Nebraska Medical School (Omaha, USA), and an advocate for those with sacroiliac joint pain, publishing multiple papers on the joint. Dall edited the textbook Surgery...
Recovery after severe spinal cord injury is notoriously fraught, with permanent paralysis often the result. In recent years, researchers have increasingly turned to stem cell-based therapies as a potential method for repairing and replacing damaged nerve cells. They have...
Spinal Elements, a spine technology company, has announced the release of its Clutch interspinous process device. This new product further enhances the breadth of Spinal Elements’ thoracolumbar portfolio and offers surgeons more options for treatment of various posterior thoracolumbar...
Percutaneous vertebroplasty does not result in statistically significant greater pain relief than a sham procedure, reports a study detailing the results of the VERTOS IV trial, published in the British Medical Journal (BMJ). This study followed patients with acute...
Michael Jackson's gravity-defying Smooth Criminal dance move, which wowed live audiences and inspired new forms of dancing, was down to core strength and an illusion, neurosurgeons write in The Journal of Neurosurgery: Spine. Dubbed the anti-gravity tilt, the seemingly impossible...
In a small cohort of patients, spinal cord stimulation has been shown to restore volitional movement in select patients with paraplegia, after intensive therapy. This was the result presented by winner of the Philip L Gildenberg Resident Award, David...
A change in policy allowing overlapping surgery decreases length of stay in an academic, safety net hospital. This is the conclusion of Anthony DiGiorgio (Department of Neurosurgery, Louisiana State University Health Sciences Center, New Orleans; Department of Neurosurgery, University...
Researchers trying to help people suffering from paralysis after a spinal cord injury or stroke mapped critical brain-to-spinal cord nerve connections that drive voluntary movement in forelimbs, a development that scientists say allows them to start looking for specific...
A new study led by Johns Hopkins researchers adds to growing evidence that patients underuse non-opioid pain relievers to supplement opioid pain management after spine and joint surgery. A report on the findings, which also shows that patients improperly store and dispose...
DiscGenics, a clinical stage regenerative medicine company, has announced the first patient has been treated in its phase I/II US clinical trial of IDCT for mild-to-moderate degenerative disc disease. The treatment took place at Carolina Neurosurgery and Spine Associates...
Infuse Bone Graft (Medtronic) has gained US Food and Drug Administration (FDA) approval in new spine surgery indications. InfuseBone Graft is now approved for use with additional spinal implants made of polyetheretherketone (PEEK) in oblique lateral interbody fusion (OLIF...
Auto-registration is better than point-to-point registration with respect to clinical accuracy when using the same active infrared navigation system during spinal surgery. This is the conclusion of the first study to compare the difference between the two methods with...
Highlights: Percutaneous vertebroplasty does not result in statistically significant greater pain relief than a sham procedure, according to the most recent results of the VERTOS IV trial Surgeons’ procedural choices have strong influence on risk of distal junctional kyphosis ...
The Scottish Medicines Consortium (SMC) has recommended the routine funding of Spinraza (nusinersen) for the treatment of symptomatic type 1 5q spinal muscular atrophy (SMA) (infantile onset). The acceptance comes after the SMC took just four months to review...
EOS imaging, a company specialising in 2D/3D imaging for orthopaedics, has announced the installation of an EOS system at the Queensland X-Ray radiology practice in the Gold Coast Private Hospital in Southport, Gold Coast, Australia. The system placement is...
A recent study detailing the cellular mechanism powering the neuronal regenerative capacities of axolotls (otherwise known as Mexican salamanders) hopes to find new leads in the treatment of spinal cord injury. Lead researcher Karen Echeverri (Department of genetics, cell...
Wearable robotics do not eliminate stress—they just shift it to other parts of the body. This is the finding of a study in which researchers tested a commercially available exoskeleton—a Steadicam vest with an articulation tool support arm—typically worn...
Highlights: New study offers hope for recovered motor function in patients with chronic spinal cord injury New algorithm decodes spine oncology treatment Experimental therapy restores nerve insulation damaged by autoimmune disease Minimally invasive TLIF procedure results in shorter hospital...
Stryker’s 3D-printed Tritanium In-Growth Technology continues to impact spinal surgery. A novel, highly porous titanium material designed for bone in-growth and biological fixation1, Tritanium was first introduced to spinal surgeons in 2016 when Stryker’s Spine division launched the Tritanium...
This article is sponsored by EIT, LLC. Emerging Implant Technologies (EIT): Cellular Titanium® for improved fusion results Frustration at the clinical shortcomings of existing cage designs and materials on the market provided the impetus for the creation of EIT Cellular Titanium®....
Designed by Columbia Engineers, the robotic spine exoskeleton (RoSE) is the first device to take in vivo measurements of torso stiffness and to characterise the three dimensional stiffness of the human torso. RoSE could lead to new treatments for...
Neurokinex (charity number 1169964)—the first and only international community fitness and wellness affiliate of the Christopher and Dana Reeve Foundation’s NeuroRecovery Network (NRN)—has opened Neurokinex Kids to help children living with paralysis. This Gatwick-based facility provides children in the...
The International Society for the Advancement of Spine Surgery (ISASS) named Belgian surgeon Marek Szpalski (Iris South Hospitals/Molière Longchamp, Brussels, Belgium) society president for the year 2018—2019 at their annual conference last week (10–13 April, Toronto, Canada). Szpalski is taking...
Two preclinical studies of IDCT, an allogenic (donor-derived), non-invasive cell therapy for the treatment of degenerative disc disease (DDD), demonstrate that proprietary discogenic cells, the active ingredient of IDCT, are safe and non-tumor forming. DiscGenics, a clinical stage regenerative...
Positive interim results of a retrospective analysis of the Luna 3D multi-expandable interbody fusion system were announced by Benvenue Medical at the Annual Meeting of the AANS/ CNS Section on Disorders of the Spine and Peripheral Nerves (14—17 March,...
The Tritanium C anterior cervical cage, a 3D-printed interbody fusion cage from Stryker’s Spine division intended for use in the cervical spine, has been implanted by 311 surgeons in more than 1,770 procedures across the USA since its introduction...
Gauthier Biomedical, a manufacturer of orthopaedic instruments and medical devices, has announced that it is the first company to achieve 510(k) approval by the US Food and Drug Administration (FDA) to market an electronic torque indicating device. Intellitorq (ITQ)...
Mainstay Medical, a medical device company focused on bringing to market ReActiv8, an implantable restorative neurostimulation system to treat disabling chronic low back pain, has provided an update on its application for the admission of ReActiv8 to the Australian...
Life Spine, a privately held medical device company based in Huntley, Illinois, has announced the first clinical use of SENTRY 2 lateral plating system, by Tien Le (NeuroSpine Center, Tampa, USA). The SENTRY 2 lateral plating system, along with the...
RTI Surgical celebrates a significant global milestone: providing more than eight million biologic implants processed through the company’s proprietary sterilisation processes with zero confirmed incidence of implant-associated infection. In 2017 alone, RTI distributed more than 600,000 biologic implants—helping surgeons...
CTL Medical has recently secured clearance from the US Food and Drug Administration (FDA) to market its new Seurat Universal pedicle screw system for the practice of spinal fusion surgery. This is the second FDA clearance for the company in...
MRI analysis of patients who received intradiscal injections of human dermal fibroblasts shows significant improvement in disc height after six months, the latest evidence from SpinalCyte demonstrates. The company say this suggests there is a quantifiable regenerative process stimulated...
CTL Medical, a Dallas-based medical device manufacturing and service company, has secured US Food and Drug Administration (FDA) clearance and approval to market its new MATISSE Titanium-PEEK ACIF cage system with the company’s proprietary TiCro surface technology in the...
The NuVasive porous polyether-ether-ketone (PEEK) material shows minimal surface damage upon impaction compared to titanium-coated devices, concludes a study recently published in The Spine Journal. NuVasive has announced the results of the study, which compares the impaction durability of conventional...
The Scoliosis Research Society (SRS) has partnered with Globus Medical, K2M, Medtronic, NuVasive, Zimmer Biomet, and the International Spine Study Group Foundation (ISSGF) to provide continued funding and research infrastructure for the Adult Symptomatic Lumbar Scoliosis (ASLS) II study. The...
Analytic software developed by orthopaedic trauma surgeons at NYU Langone Health accurately identifies which middle-aged and elderly patients face a greater mortality risk following surgery for an orthopaedic fracture, according to a new study. PersonaCARE is a predictive, deep-learning software...
In an elderly Chinese population, intervertebral disc narrowing over a four-year period is associated with the presence of osteoporosis, and is greater in women than men. These results, initially published in the journal Spine, were the conclusions of a...
Cerapedics, a privately-held orthobiologics company, has announced the company received approval from the US Food and Drug Administration (FDA) to initiate an investigational device exemption (IDE) clinical trial evaluating the safety and efficacy of P-15L peptide enhanced bone graft...
Despite claims that helmets do not protect the cervical spine during a motorcycle crash and may even increase the risk of injury, researchers from the University of Wisconsin Hospitals and Clinics in Madison found that, during an accident, helmet...
A new study, published in the journal Stem Cell Reports, has revealed that the human brain's tiniest blood vessels can activate genes known to trigger spinal motor neurons, prompting the neurons to grow during early development. The findings could...
Camber Spine, a leading innovator in spinal and medical technologies, has announced the first surgeries using the company's proprietary SPIRA™-C Open Matrix Cervical Interbody device, a unique, interbody fusion implant consisting of spiral support arches and Surface by Design™ technology. The...
Spineology has announced that enrollment is now complete in the company's Spineology Clinical Outcomes Trial (SCOUT) clinical trial. The SCOUT IDE, conducted under an FDA-approved protocol, is a prospective, multicentre non-randomised performance goal investigation, designed to evaluate safety and effectiveness...
Dimitri Filippiadis and Alexis Kelekis (both Department of Radiology II, Attikon University Hospital, Athens, Greece) here detail the history and future of percutaneous vertebroplasty and kyphoplasty, and discuss the findings of the 2016 VAPOUR trial. This demonstrated that patients...
A team lead by Denis Evseenko (Department of Orthopaedic Surgery, University of Southern California, Los Angeles, USA) hopes to delay or reduce the need for joint replacement surgery in osteoarthritis patients with an injection. Osteoarthritis is also known as degenerative joint...

Charles Fisher

Charles Fisher (University of British Columbia, Canada) was honoured in 2016 as one of the top 28 spine surgeons in North America, a highlight of a career spanning four decades. Head of the Combined Neurosurgical and Orthopaedic Spine Programme...
Daniel Spencer is a business manager at Charlton Morris, an executive search firm specialising in the medical space. Here, he argues that 3D printing is transforming the spinal implant marketplace, and will play an ever-increasing role in shaping the...
Scientists at Cincinnati Children’s Hospital Medical Centre report an experimental molecular therapy that restores insulation around peripheral nerves in mice, improves limb function, and results in less observable discomfort. These results were initially described in Nature Medicine in February...
Spinal muscular atrophy (SMA) patients treated with SPINRAZA (nusinersen) have experienced stabilised or improved motor function, contrary to the natural course of the degenerative disease, Biogen and Ionic Pharmaceuticals have announced. This is the end of study result from...
Varun Rimmalapudi and Jeff Buchalter (both Gulf Coast Pain Institute, Pensacola, USA) respond to an article printed in the October issue of Spinal News International: "Radiofrequency denervation fails to provide clinically important chronic low back pain improvement". The results were...
Experts explain their approach to treating patients who are living longer with cancer that has spread to the spine, as the options for metastatic spine tumours increase. Every kind of cancer can spread to the spine, yet two physician-scientists who...
Eli Lilly and Company has announced that Taltz (ixekizumab) met the primary and all key secondary endpoints in COAST-V, a Phase three study evaluating the safety and efficacy of Taltz for the treatment of Ankylosing Spondylitis (AS), also known as radiographic...
The results of a two-year study demonstrate decompression with coflex interlaminar stabilisation extends the durability and sustainability of a decompression procedure. coflex is the first and only motion-preserving, minimally-invasive treatment approved for moderate to severe spinal stenosis post-decompression. The European...
EOS imaging, a company specialising in 2D and 3D imaging and data solutions for orthopaedics, has announced the installation of an EOS system at the Beijing Jishuitan Hospital, a top-ranking speciality orthopaedic hospital in China. This installation follows the first two...
Simplify Medical, a company focused on cervical spinal disc arthroplasty and maker of the Simplify cervical artificial disc, has announced a second tranche of its Series B financing of US$23.25 million, completing the oversubscribed round totalling US$44.25 million. The lead...
  Bioventus, a global leader in orthobiologic solutions, has entered into an agreement with LifeLink Tissue Bank, a division of LifeLink Foundation, to co-develop a next generation bone allograft solution for use in spine and trauma surgery. Terms of the...
Spinal muscular atrophy sufferers are a step closer to accessing vastly life-improving treatment following the formal National Institute for Health and Care Excellence (NICE) invitation to Biogen to submit SPINRAZA (nusinersen) for assessment via the Single Technology Appraisal route....
Spine technology company Astura Medical has today announced the completion of the initial surgeries and full commercial release for its Bridalveil Occipital-Cervico-Thoracic (OCT) system. The first cases were successfully completed at multiple US hospitals. David Ou-Yang (The spine centre,...
The Food and Drug Administration (FDA) has today issued the final rule on “human subject protection; acceptance of data from clinical investigations for medical devices”. The rule updates the FDA’s standards for accepting clinical data from clinical investigations conducted...
The nerve circuits that enable people to walk first appeared more than 400 million years ago in fish whose descendants still walk the seafloor on their fins. This is the finding of a study led by researchers from NYU...
Orthofix International, a global medical device company focused on musculoskeletal healing products, has announced the 510(k) clearance and US limited market launch of the FORZA XP Expandable Spacer System. Designed to restore normal disc height in patients suffering from degenerative...
Mount Sinai researchers have found a possible link between a poor diet and back injuries, especially in women. The study suggests that following a specific type of diet that excludes fast foods and highly processed foods could decrease vertebral...
  Researchers report the successful use of a novel therapeutic strategy to enhance forelimb recovery in mice with chronically injured spinal cords. The findings were presented by Hidenori Suzuki (Department of Orthopaedics, Yamaguchi University graduate school of medicine, Ube, Japan)...
The first cases using the Triojection system to treat spinal disc herniations in Germany were recently performed, Minimus Spine Inc. has announced. The cases were performed by Thomas Vogl, (Institute for Diagnostic and Interventional Radiology, J.W. Goethe University Hospital,...
  New research using unbiased serum proteomics, a state-of-the-art technique in orthopaedics, aims to predict which cervical radiculopathy patients will fail conservative treatment and consequently require surgery. The principal investigator Steven Presciutti (Department of Orthopaedics, Emory University School of Medicine,...
Johnson & Johnson has formed the Johnson & Johnson Institute, bringing together 26 professional educational facilities across four continents. The Johnson & Johnson Institute also includes “a network of online education and partnerships across multiple specialties,” says Ian Davies, vice...
Kleiner Device Labs has announced full commercial availability of a new spinal bone graft delivery tool, the KG 1, featuring a patented design that facilitates less-invasive procedures and has been proven in clinical testing to reduce spinal fusion failure...
Life Spine announced on 16 January that revenues for ProLift Expandable Spacer System grew by 493% for 2017 as compared to 2016. “With the introduction of ProLift to the market in 2016, we have consistently experienced monumental sales growth...
Spineology has announced the completion of the first post-market study cases using its recently FDA-cleared Duo Lumbar Interbody Fusion System. In October, the company announced the initiation of this prospective, post-market lateral interbody fusion study designed to evaluate patient...

Shay Bess

Founder and president of the International Spine Study Group Foundation, Shay Bess credits the friendships and research opportunities he has had through his career with the meaning and satisfaction he has found through his work. He speaks to Spinal...
New research has identified that inciting events may be associated with a positive outcome for patients diagnosed with lumbar facet joint pain. Charles Odonkor (Associate Faculty, International Rehabilitation Forum, Johns Hopkins University, Baltimore, USA) presented the findings at the...
Highlights: New imaging technique to improve assessment of surgical patients with lumbar degeneration Precipitating events associated with successful radiofrequency ablation of lumbar facet joint pain Peptide enhanced bone graft outperforms autograft at two years Profile: Shay Bess https://o6xux43a6gs4eidym2svvhon-wpengine.netdna-ssl.com/wp-content/uploads/sites/11/2018/01/45-Spinal-News_lowres_US_v1.pdf